PMID: 11339415May 8, 2001Paper

Effect of mouth washing on the

Journal of Gastroenterology and Hepatology
T H LeeT H Wang

Abstract

Mouth washing is often mentioned as a possible method to eliminate the interference of urease activity in the oral cavity before the [13C]-urea breath test (UBT). However, the effectiveness of mouth washing prior to testing has not been demonstrated clearly in the literature. Thus, the present study was designed to examine the consistency of the [13C]-UBT and the effects of mouth washing on it. A total of 101 healthy volunteers underwent the [13C]-UBT three times. The first and second tests used a standard protocol and collected samples at 5, 10, 15 and 30 min. In the third test, the procedure was the same except that mouth washing was omitted. We used 5 permil (/1000) as the cut-off value and there were 21 (20.8%) positive cases. The kappa values for the samples collected at 5, 10, 15 and 30 min between the first and second tests were 0.68, 0.97, 1 and 1, respectively, and all showed good consistency, except for the sample collected at 5 min. Judging from the mean value of the [13C] enrichment of the first and second tests (with mouth washing) and the third test (without mouth washing), 50 (63.3%), 15 (18.8%), 0 and 0 cases at 5, 10, 15 and 30 min, respectively, changed from negative to positive. There were 14 (17.5%) and six ...Continue Reading

References

Aug 1, 1971·Journal of Periodontology·S S Socransky, S D Manganiello
Jul 8, 1982·The New England Journal of Medicine·P A Mackowiak
Feb 7, 1994·NIH Consensus Statement
Jun 1, 1994·Gut·J C Atherton, R C Spiller
Jan 1, 1996·Scandinavian Journal of Gastroenterology. Supplement·S J Rune
Jan 1, 1996·Scandinavian Journal of Gastroenterology. Supplement·J Hansky

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Citations

Oct 22, 2003·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·T H LeeT H Wang
Jun 10, 2009·Best Practice & Research. Clinical Gastroenterology·Barbara Braden
Mar 16, 2018·The Cochrane Database of Systematic Reviews·Lawrence Mj BestKurinchi Selvan Gurusamy
Dec 17, 2015·World Journal of Gastroenterology : WJG·Shu-Ming YinZhi-Jun Bao

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