Effect of MRI Versus MDCT on Milan Criteria Scores and Liver Transplantation Eligibility

AJR. American Journal of Roentgenology
Nassir RostambeigiDonna D'Souza

Abstract

The Milan criteria for the selection of patients with hepatocellular carcinoma (HCC) for liver transplantation were originally based on the findings of contrast-enhanced CT examinations. Studies have shown improvement in HCC detection of using contrast-enhanced MRI instead of CT, but they have provided little information on the potential downstream effect on patient management that might result from discrepant imaging findings. We sought to assess the effect of discrepant imaging findings on patient eligibility to undergo liver transplantation. From 2006 to 2013, patients with a diagnosis of HCC who underwent both MDCT and MRI examinations within a 40-day period were studied retrospectively. All examinations were independently reviewed by two abdominal radiologists who recorded the number, diameter, and location of each lesion. Secondary confirmation of the lesions was made on the basis of histopathologic findings, diffusion restriction on DWI, increased T2 signal intensity, lesion growth, presence of fat, uptake of ethiodized oil, or a combination of these findings. Sixty-four patients (48 men and 16 women; mean age, 62 years) met the criteria for inclusion in the study. Of the 129 lesions identified by MRI, only 102 of these ...Continue Reading

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Citations

Aug 7, 2017·Abdominal Radiology·Tina SanghviAndrew Taylor
Jun 29, 2018·Journal of Clinical and Translational Hepatology·Shamar YoungTina Sanghvi
Jul 1, 2017·Cancer Imaging : the Official Publication of the International Cancer Imaging Society·Mustafa KurucayWolfgang M Thaiss
Jun 23, 2020·Cancer Biomarkers : Section a of Disease Markers·Ihab BarsoumMohamed A A Bassiony

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