Effect of mycoplasma on interferon production and interferon assay in cell cultures.

Journal of Bacteriology
D Armstrong, K Paucker

Abstract

Armstrong, D. (The Children's Hospital of Philadelphia, Philadelphia, Pa.), and K. Paucker. Effect of mycoplasma on interferon production and interferon assay in cell cultures. J. Bacteriol. 92:97-101. 1966.-The influence of mycoplasma on the production and action of interferon was studied in cultures of both L and human embryonic kidney (HEK) cells. Mycoplasma hominis 1, the Negroni agent, and the F12 mycoplasma were used for infection of L cells, and M. hominis 1 and M. pneumoniae for inoculation of HEK cells. All strains were capable of multiplication in the culture systems employed. None produced detectable levels of interferon, and responsiveness of the cells to induction of interferon by virus remained unaltered. Infection with mycoplasma did not impair the sensitivity of the cells to the action of interferon, nor was the replication of vesicular stomatitis virus noticeably diminished.

References

Nov 1, 1965·Virology·F I Yershov, V M Zhdanov
Jan 1, 1963·Virology·K CANTELL, K PAUCKER
Apr 11, 1964·British Medical Journal·G NEGRONI
Feb 1, 1964·Journal of General Microbiology·M BUTLER, R H LEACH
Nov 14, 1964·British Medical Journal·N R GRIST, H MATTHEW
Jul 1, 1965·The Journal of Pediatrics·L A GLASGOW
Aug 1, 1965·Journal of Bacteriology·N L SOMERSON, M K COOK

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Citations

Jun 1, 1971·Bacteriological Reviews·E Stanbridge
Mar 1, 1971·Infection and Immunity·M Worthington, S A Aaronson
Dec 1, 1974·Infection and Immunity·C R RinaldoL A Glasgow
Dec 11, 1975·Infection and Immunity·B C ColeL A Glasgow
Jul 1, 1976·Infection and Immunity·B C ColeL A Glasgow
Nov 1, 1973·Infection and Immunity·C R RinaldoL A Glasgow

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