Effect of Nasogastric Tube Feeding vs Nil per Os on Dysmotility in Acute Pancreatitis: Results of a Randomized Controlled Trial

Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition
Jiemin MaMaxim S Petrov

Abstract

Evidence from animal studies suggests that gastrointestinal motility is impaired in acute pancreatitis. Enteral nutrition, and more specifically nasogastric tube feeding, has emerged as a key treatment modality in patients with acute pancreatitis, but its effect on motility has not been investigated in this setting. The aim was to validate the Gastroparesis Cardinal Symptom Index (GCSI) in patients with acute pancreatitis and determine the effect of nasogastric tube feeding on GCSI. The study design was a randomized controlled trial. Patients were allocated to nasogastric tube feeding or nil per os within 24 hours of hospital admission. GCSI data from before randomization to 72 hours after randomization were analyzed. The test-retest reliability analysis was used to calculate Cronbach's α. Seventeen patients were randomized to nasogastric tube feeding and 18 to nil per os. Overall, the total GCSI score significantly decreased over the study (F = 8.537; P = .001) but was not significantly different between the 2 study groups during hospitalization (F = 1.159; P = .322). However, patients on nasogastric tube feeding did show improved appetite compared with nil per os (F = 3.526; P = .036). The GCSI was found to be a reliable tool...Continue Reading

References

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Citations

Oct 25, 2016·PloS One·Andrea SzentesiUNKNOWN Hungarian Pancreatic Study Group
Mar 10, 2017·Scandinavian Journal of Gastroenterology·Maxim S Petrov
Jun 20, 2018·Minerva gastroenterologica e dietologica·Fuchsia D Gold-SmithMaxim S Petrov
Jun 25, 2016·Current Opinion in Clinical Nutrition and Metabolic Care·Arved Weimann, Thomas W Felbinger
Jan 30, 2018·JPEN. Journal of Parenteral and Enteral Nutrition·Desheng QiMilin Peng
Oct 16, 2020·Clinica Chimica Acta; International Journal of Clinical Chemistry·Wandia Kimita, Maxim S Petrov

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Software Mentioned

GCSI
SPSS

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