Effect of near ambient exposures to sulfur dioxide and ferrous sulfate particles on murine pulmonary defense mechanisms

Archives of Environmental Health
E GoldsteinB Tarkington

Abstract

An infectivity model was used to test the safety margins for presently established air quality standards for sulfur dioxide and sulfate particles. Mice and rats were exposed to atmospheres of sulfur dioxide and mono-disperse ferrous sulfate particles from 3 to 6 times the standard for 17 hr prior to, or 4 hr after infection with aerosols of Staphylococcus aureus or Group C Streptococci. Exposure to these concentrations of pollutants did not impair the rodents' ability to ingest and inactivate the minimally virulent Straphylococcus or enhance the virulence of the Group C Streptococci. Insofar as these results can be extrapolated to man, the present air quality standards for sulfur dioxide and sulfate particles are protective in regard to respiratory bacterial infection.

References

Oct 1, 1977·Environmental Research·R EhrlichD E Gardner
Jun 1, 1976·Environmental Research·K Biersteker
Aug 1, 1975·Archives of Environmental Health·J D HackneyA Fischer
Nov 1, 1975·Archives of Environmental Health·G A FairchildD Coffin
Aug 1, 1974·Environmental Health Perspectives·D P Rall
Apr 1, 1973·Archives of Environmental Health·E GoldsteinP D Hoeprich
Jan 1, 1973·Internationales Archiv Für Arbeitsmedizin·G von NiedingK Koppenhagen
Sep 1, 1973·Archives of Environmental Health·J G FrenchM Hertz
Sep 1, 1973·Archives of Environmental Health·B G FerrisJ M Peters
Sep 1, 1973·Archives of Environmental Health·M HazuchaD V Bates
Feb 1, 1974·Archives of Environmental Health·E GoldsteinB Tarkington
May 1, 1974·Archives of Environmental Health·D I HammerP F Wehrle
Sep 1, 1974·The Journal of Clinical Investigation·E GoldsteinD Warshauer
Sep 1, 1969·Journal of the Air Pollution Control Association·M O Amdur
Jun 1, 1971·Archives of Internal Medicine·E GoldsteinC Eagle
Apr 1, 1968·Archives of Environmental Health·M O Amdur, D Underhill
Jan 1, 1964·The Journal of Experimental Medicine·G M GREEN, E H KASS
Nov 1, 1961·The Journal of Infectious Diseases·M R PURVISR EHRLICH
Jul 1, 1947·The American Journal of Physiology·A C GUYTON

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Citations

Sep 1, 1987·European Journal of Epidemiology·S R Kamat, V B Doshi
May 1, 1981·Archives of Environmental Health·R L SherwoodE Goldstein
Dec 1, 1982·Environmental Research·E Azoulay-DupuisM C Blayo
Jul 1, 1983·Journal of Toxicology and Environmental Health·C AranyiF J Miller
May 1, 1989·Toxicology and Industrial Health·J R Withey

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