Effect of new-onset atrial fibrillation on cause-specific late mortality after coronary artery bypass grafting surgery

European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery
Thomas A SchwannRobert H Habib

Abstract

Postoperative atrial fibrillation (POAF) is a common complication after coronary artery bypass grafting. Although transient, POAF is linked to increased late mortality. We hypothesized that POAF increases late cerebrovascular (CeV) and composite cerebrovascular/cardiovascular/vascular (CV* = CeV + CV + Other-V) but not non-cardiovascular (Non-CV) mortality. We analysed 8807 non-salvage coronary artery bypass grafting patients (1994-2011). Fifteen-year and time-segmented (early, 0-1 year; intermediate, 1-6 years and late, 6-15 years) all-cause and cause-specific mortality were compared for POAF versus No-POAF patients. Corresponding POAF versus No-POAF adjusted hazard ratios [AHRs (95% confidence interval, CI)] were derived using the competing risk Cox regression. POAF occurred in 1992 (23%) patients. Complications other than POAF occurred in 1875 (21%) patients but were more frequent among POAF patients (31% vs 18%; P < 0.001). Overall mean follow-up was 9 ± 4 years. POAF patients had a higher 15-year unadjusted mortality (53% vs 39%; P < 0.001) and were consequently associated with higher adjusted all-cause [AHR (95% CI) = 1.23 (1.14-1.33)] and composite cardiovascular [CV*: AHR (95% CI) = 1.15 (1.02-1.30)] mortality. The tren...Continue Reading

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Citations

Dec 18, 2019·BMC Cardiovascular Disorders·Maciej RachwalikMarek Jasiński
Jul 21, 2020·The Annals of Thoracic Surgery·Rachel EikelboomRakesh C Arora
May 7, 2021·The Journal of Thoracic and Cardiovascular Surgery·Tulio CaldonazoUNKNOWN POAF-MA Group
Jan 14, 2021·The Annals of Thoracic Surgery·Victor NauffalPatrick T Ellinor

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