PMID: 2511657Sep 1, 1989Paper

Effect of nursing on Brucella abortus infection of mammary glands of goats

Veterinary Pathology
V P MeadorN F Cheville

Abstract

Eight 1-year-old, goats were inoculated intravenously with Brucella abortus (B. abortus) on the day of parturition and necropsied at 28 days after inoculation. Four nursed their kids and four did not (milk was not removed from the udders). Tissues and fluids were examined by bacterial isolation, light microscopy, and serologic methods. Nonnursing goats had high titers of brucellae (less than or equal to 10(8) organisms/ml) in milk (brucellae were isolated from four of four udders), had marked enlargement of supramammary lymph nodes, and had lymphoplasmacytic and histiocytic interstitial mastitis. Immunoperoxidase staining revealed that brucellae were primarily in macrophages and neutrophils of the mammary alveolar and ductal lumens and in macrophages of the subcapsular sinuses of the supramammary lymph node. In contrast, nursing goats excreted brucellae intermittently at low concentrations (less than 10(3) organisms/ml) in milk; brucellae were isolated at necropsy from one of four udders; supramammary lymph nodes were not enlarged; and mammary lesions were not seen. Brucellae were detected in more tissues other than the udder, and serum anti-Brucella antibody titers were higher in nonnursing goats than in nursing goats. The pre...Continue Reading

References

Aug 1, 1987·Australian Veterinary Journal·L A CornerH Iyer
Feb 1, 1972·The Journal of Dairy Research·C L ThomasT M Higgs
Oct 1, 1959·The Journal of Pathology and Bacteriology·J M PAYNE

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Citations

Feb 13, 2021·Pathogens·Gabriela González-EspinozaJean-Pierre Gorvel

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