Effect of oat saponins and different types of dietary fibre on the digestion of carbohydrates

The British Journal of Nutrition
G Onning, N G Asp

Abstract

The effects of oat saponins (a mixture of avenacosides A and B) and dietary fibre (cellulose and guar gum) on the disaccharidase activities in the proximal small intestine of the rat were investigated. The influence of avenacosides A and B on the activity of disaccharidases and alpha-amylase (EC 3.2.1.1) was also studied in vitro. In vivo, oat diets with three avenacoside contents (negligible, normal and twice normal) were used. No significant differences in sucrase (EC 3.2.1.48), maltase (EC 3.2.1.20), trehalase (EC 3.2.1.28) and lactase (EC 3.2.1.21) activities were found between the oat groups after 19 d feeding. The rats that were given cellulose tended to have higher disaccharidase activities compared with the other groups. The avenacosides inhibited the lactase activity significantly in vitro while no or small effects on the other disaccharidases were found. In contrast, the in vitro hydrolysis of starch by alpha-amylase was increased in the presence of saponins, probably due to their detergent effect. Thus, the in vitro studies showed that the avenacosides could influence the enzyme activities. In vivo, these effects are probably minor due to the low avenacoside concentrations found in oats.

References

Jan 1, 1987·Critical Reviews in Food Science and Nutrition·K R PriceG R Fenwick
May 1, 1986·The British Journal of Nutrition·I T Johnson, J M Gee
Jan 1, 1968·Analytical Biochemistry·A Dahlqvist
Jul 1, 1982·The Journal of Nutrition·P L Farness, B O Schneeman
Jan 1, 1982·Digestion·L L Thomsen, C Tasman-Jones
May 1, 1983·Journal of Agricultural and Food Chemistry·N G AspM Siljeström
Jan 1, 1984·Advances in Experimental Medicine and Biology·A L LivingstonL S Tsai
Jun 1, 1984·The American Journal of Clinical Nutrition·J A StoryG V Vahouny
Feb 1, 1995·The British Journal of Nutrition·G Onning, N G Asp

❮ Previous
Next ❯

Citations

Dec 17, 2008·Nutrition Research Reviews·Danielle RyanKevin Robards
Oct 23, 1997·Journal of the American Dietetic Association·J A Marlett, T F Cheung
Jul 23, 2013·Food Chemistry·Łukasz PecioAnna Stochmal
Aug 11, 2016·Journal of Agricultural and Food Chemistry·Jitendra KumarNarendra Pratap Singh
Jan 10, 2017·Molecular Nutrition & Food Research·Shengmin Sang, YiFang Chu
Dec 8, 2006·European Journal of Clinical Nutrition·H MäkeläinenT Sontag-Strohm
Dec 6, 2007·European Journal of Clinical Nutrition·J H Cummings, A M Stephen

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.