PMID: 9426376Jan 14, 1998Paper

Effect of obesity and regional adiposity on the QTc interval in women

International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity
J J Park, P D Swan

Abstract

To determine whether differences in body fat composition and body fat distribution patterns are associated with a prolongation of the corrected QT interval for heart rate (QTc) on the electrocardiogram (EKG) during rest and exercise. Cross-sectional evaluation of the Qtc interval in three groups of premenopausal women during rest and two exercise conditions (50% VO2 max and VO2 max). Thirty-one healthy women with a mean age of 35 y (27-44 y) were classified as either obese (n = 22; percent body fat [%BF] > 30%) or nonobese (NO; n = 9; %BF < or = or 27%) by hydrostatic weighing. Obese subjects matched for age and %BF were grouped by waist to hip ratio (WHR) into two groups: upper body obesity (UBO; n = 11; WHR > or = 0.85) and lower body obesity (LBO; n = 11; WHR < or = 0.75. RR and QT intervals were measured in a double-blind design with the aid of calipers and magnifying lens for seven consecutive beats in lead II from a 12-lead EKG at a paper speed of 25 mm/sec. Five consecutive cardiac cycles excluding the longest and shortest RR and QT intervals were averaged and calculated for QTc interval using Bazett's formula. Mean QTc intervals were significantly different (P < 0.001) across the groups for each condition. For all condi...Continue Reading

Citations

May 20, 2014·The Kaohsiung Journal of Medical Sciences·Kai-Ting ChangSheng-Hsiung Sheu
Mar 10, 2016·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·J OmranM A Alpert
Oct 26, 2005·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·M A FraleyM A Alpert
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May 4, 2010·The Journal of Clinical Hypertension·Andrew GrandinettiPhillip Low
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May 8, 2002·The Journal of Clinical Endocrinology and Metabolism·Grazia Maria CorbiDario Giugliano
Jul 23, 2020·Artificial Cells, Nanomedicine, and Biotechnology·Haishan ChenHequn Zou
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Dec 20, 2018·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·Yuvreet KaurDavid Meyre
Jun 7, 2021·BMC Cardiovascular Disorders·Mohammad Hosein YazdanpanahShiva Dadvand

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