Effect of obesity on laparoscopy-assisted distal gastrectomy compared with open distal gastrectomy for gastric cancer

Journal of Surgical Oncology
Hirochika MakinoItaru Endo

Abstract

This study compared surgical outcomes between patients undergoing laparoscopy-assisted distal gastrectomy (LADG) and those undergoing open distal gastrectomy (ODG) from the viewpoint of obesity. Between June 2002 and May 2008, 146 patients with preoperatively diagnosed early gastric cancer who underwent LADG (n = 90) or ODG (n = 56) were enrolled in this study and compared in terms of clinicopathological findings and operative outcome. The visceral fat area (VFA) and subcutaneous fat area (SFA) were assessed as identifiers of obesity using FatScan software. The relationship between obesity and operative outcomes after LADG and ODG was evaluated. There were no significant correlations between intraoperative blood loss (IBL) and any obesity-related factors, or between operation time (OT) and any obesity-related factors in the LADG group. There was a significant correlation between IBL and BMI (r = 0.486, P = 0.0001), IBL and VFA (r = 0.456, P = 0.0003), IBL and SFA (r = 0.311, P = 0.0193), OT and BMI (r = 0.406, P = 0.0017), OT and VFA (r = 0.314, P = 0.0178), and between OT and SFA (r = 0.382, P = 0.0034) in the ODG group. LADG may be a useful operative manipulation that is not influenced by obesity, whereas ODG may be influence...Continue Reading

References

Feb 1, 1993·Endocrine Reviews·C BouchardP Mauriège
Jul 1, 1997·The British Journal of Radiology·K AkahoshiT Kabemura
Apr 6, 1999·Radiology·T YoshizumiY Matsuzawa
Sep 14, 2000·Gynecologic Oncology·G H EltabbakhL L Garafano
Oct 17, 2001·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·D M ParkinS S Devesa
Nov 15, 2001·Gastric Cancer : Official Journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association·UNKNOWN Japanese Gastric Cancer Association
May 2, 2002·Gastric Cancer : Official Journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association·Satoshi InagawaKatashi Fukao
Aug 8, 2002·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·N YoshiikeS Inoue
Nov 7, 2002·Circulation Journal : Official Journal of the Japanese Circulation Society·UNKNOWN Examination Committee of Criteria for 'Obesity Disease' in Japan, UNKNOWN Japan Society for the Study of Obesity
May 24, 2003·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Anthony J SenagoreC Victor W Fazio
Mar 5, 2005·Gastric Cancer : Official Journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association·Makoto KuboMitsuru Sasako
Jul 11, 2006·European Journal of Gastroenterology & Hepatology·Seigo KitanoNorio Shiraishi
Dec 6, 2006·Annals of Surgical Oncology·Toshimasa TsujinakaUNKNOWN Gastric Cancer Surgery Study Group of Japan Clinical Oncology Group
Jan 20, 2007·Gastric Cancer : Official Journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association·Ichiro OdaShigeaki Yoshida
Jan 20, 2007·Gastric Cancer : Official Journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association·Ki-Han KimHyung-Ho Kim
Oct 24, 2007·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Hiroyuki YamadaKenichi Sugihara
Jun 25, 2008·Surgical Laparoscopy, Endoscopy & Percutaneous Techniques·Chikara KunisakiHiroshi Shimada

❮ Previous
Next ❯

Citations

Feb 22, 2012·Gastric Cancer : Official Journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association·Roderich E Schwarz
Aug 1, 2012·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Masanori TokunagaMasanori Terashima
Sep 6, 2013·Gastric Cancer : Official Journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association·Masanori TokunagaMasanori Terashima
Mar 14, 2014·Surgical Endoscopy·In Gyu KwonWoo Jin Hyung
Apr 9, 2011·World Journal of Surgery·Keisuke KoedaGo Wakabayashi
Aug 31, 2013·Urology·Edward IoffeReza Ghavamian
Jul 31, 2012·The Surgeon : Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland·Akira MiyakiJun Matsumoto

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.