Jan 1, 1982

Effect of obzidan on cerebral blood flow in acute cerebral ischemia

Farmakologiia i toksikologiia
L N Dorokhova


The effect of obsidan on the local cerebral circulation was studied in cats with normal brain circulation and under acute cerebral ischemia. It was demonstrated that obsidan (0.2 mg/kg) increased local cerebral circulation, while on being given in a dose of 1 mg/kg it lowered it in cats with normal brain circulation. In animals with stroke (both on the side with normal circulation and on the side of cerebral ischemia) obsidan (0.2 mg/kg) significantly decreased the local cerebral circulation and destroyed autoregulation of the brain circulation.

  • References
  • Citations


  • We're still populating references for this paper, please check back later.
  • References
  • Citations


  • This paper may not have been cited yet.

Mentioned in this Paper

Cerebral Blood Flow Imaging
Diastolic Blood Pressure
Acute Disease
Cerebrovascular Circulation
Cerebral Infarction
Dose-Response Relationship, Drug
Brain Circulation
Medicinal Plants Testing, Preclinical

About this Paper

Related Feeds

Brain Ischemia

Brain ischemia is a condition in which there is insufficient blood flow to the brain to meet metabolic demand. Discover the latest research on brain ischemia here.