Effect of on-line conductivity plasma ultrafiltrate kinetic modeling on cardiovascular stability of hemodialysis patients

Kidney International
F LocatelliC Tetta

Abstract

The aim of this multicenter, prospective, randomized cross-over study was to clarify whether on-line conductivity ultrafiltrate kinetic modeling (treatment B), as a substitute for sodium kinetic modeling, is capable of reducing intradialytic cardiovascular instability in comparison with standard treatment (treatment A), by reducing the sodium balance variability. Both treatments were performed by means of a modified hemodiafiltration technique. Treatment A was performed using fixed dialysate conductivity; treatment B made use of the dialysate conductivity derived from a conductivity kinetic model, in order to obtain an end-dialysis ultrafiltrate conductivity at each dialysis session that was equal to the mean value determined in the same patient during the four-week run-in period. Thus, during treatment B, the expected end-dialysis ultrafiltrate conductivity value of each patient should have been constant. The study was carried out according to a multicenter cross-over design of 16 weeks with two treatments (A or B), two sequences (1 = ABB and 2 = BAA), a run-in period of four weeks (period 1, treatment A), and three consecutive experimental periods of four weeks each. Analysis of variance for a cross-over design was used for t...Continue Reading

References

Jul 1, 1979·British Journal of Clinical Pharmacology·M Hills, P Armitage
Sep 1, 1991·Kidney International·L A PedriniF Locatelli
Feb 1, 1991·Kidney International·J T Daugirdas
Jan 1, 1989·Contributions to Nephrology·F LocatelliS Di Filippo
Jan 1, 1996·Blood Purification·S Di FilippoF Locatelli
Oct 1, 1996·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·C ManzoniF Locatelli
Dec 1, 1996·Journal of the American Society of Nephrology : JASN·F LocatelliS Di Filippo
Mar 1, 1997·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·M J FlaniganV S Lim

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Citations

Nov 26, 2009·Nature Reviews. Nephrology·Francesco LocatelliBenedetta Tucci
Mar 20, 2004·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Francesco LocatelliMohammed Yaqoob
Jan 6, 2005·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Francesco LocatelliPietro Zucchelli
Sep 8, 2005·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Karin MoretJeroen Kooman
Jan 31, 2012·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Raymond Vanholder
Jul 9, 2010·Nephrology·Lisa M Phipps, David C H Harris
Mar 10, 2010·Seminars in Dialysis·Francesco LocatelliAndrea Cavalli
Mar 29, 2008·Clinical Journal of the American Society of Nephrology : CJASN·Lucile MercadalThierry Petitclerc
Aug 11, 2000·Kidney International. Supplement·M J Flanigan
Aug 11, 2000·Kidney International. Supplement·F LocatelliC Manzoni
Nov 18, 2008·Néphrologie & thérapeutique·Lucile Mercadal, Thierry Petitclerc
Dec 3, 2002·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Simeone AndrulliFrancesco Locatelli
Sep 23, 2016·Expert Review of Medical Devices·Manoj K SharmaJeroen P Kooman
Oct 27, 2001·Seminars in Dialysis·S StillerH Mann
Jun 6, 2013·Blood Purification·Jeong Chul Kim, Claudio Ronco
Apr 7, 2007·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Nicholas M SelbyChristopher W McIntyre
Jul 31, 2001·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·F LocatelliE Ritz
Feb 24, 2001·Seminars in Dialysis·B F Palmer
Jun 25, 2016·The International Journal of Artificial Organs·Giustina CasagrandeMaria Laura Costantino
Mar 12, 2004·Nephrology·Moon-jae KimSeoung woo Lee

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