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Effect of oral antacid administration on the pharmacokinetics of intravenous doxycycline

Antimicrobial Agents and Chemotherapy

Apr 1, 1989

V X NguyenJ J Schentag

PMID: 2729939

Abstract

The effect of oral antacid administration on the pharmacokinetics of intravenous doxycycline was studied. In a randomized crossover design, six healthy male volunteers received an infusion of 200 mg of doxycycline hyclate on two occasions separated by 7 days. On one occasion, subjects w...read more

Mentioned in this Paper

Doxycycline Phosphate (1: 1)
Alhydrogel
Drug Interactions
Antacids
Intravenous Infusion Procedures
Paper Details
References
  • References7
  • Citations10
1
  • References7
  • Citations10
1

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Effect of oral antacid administration on the pharmacokinetics of intravenous doxycycline

Antimicrobial Agents and Chemotherapy

Apr 1, 1989

V X NguyenJ J Schentag

PMID: 2729939

DOI:

Abstract

The effect of oral antacid administration on the pharmacokinetics of intravenous doxycycline was studied. In a randomized crossover design, six healthy male volunteers received an infusion of 200 mg of doxycycline hyclate on two occasions separated by 7 days. On one occasion, subjects w...read more

Mentioned in this Paper

Doxycycline Phosphate (1: 1)
Alhydrogel
Drug Interactions
Antacids
Intravenous Infusion Procedures

Similar Papers Found In These Feeds

CRISPR Screens in Drug Resistance

CRISPR-Cas system enables the editing of genes to create or correct mutations. This feed focuses on the application of CRISPR-Cas system in high-throughput genome-wide screens to identify genes that may confer drug resistance.

Vitamin K Carboxylase & Antibiotics

Vitamin K-dependent carboxylases generate gamma-carboxyglutamic acids with malonate moieties by modifying glutamate residues in vitamin K-dependent proteins. This feed focuses on cellular mechanisms regulated by vitamin K-dependent carboxylases.

Related Papers

Antimicrobial Agents and Chemotherapy

Effect of antacid on the bioavailability of cefprozil

Antimicrobial Agents and ChemotherapyMay 1, 1992
W C ShyuR H Barbhaiya
European Journal of Clinical Pharmacology

Effects on cimetidine bioavailability of metoclopramide and antacids given two hours apart

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N BarzaghiE Perucca
Paper Details
References
  • References7
  • Citations10
1
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1
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