Effect of oral intake of capsaicinoid beadlets on catecholamine secretion and blood markers of lipolysis in healthy adults: a randomized, placebo controlled, double-blind, cross-over study.

Lipids in Health and Disease
Richard J BloomerSujata Suvarnapathki

Abstract

In the present investigation we compared blood epinephrine (EPI), norepinephrine (NE), free fatty acids (FFA) and glycerol concentrations in response to a capsaicinoid supplement or placebo in healthy adults before and after acute exercise. Twenty subjects ingested a placebo or supplement (Capsimax, OmniActive Health Technologies; 2 mg capsaicinoids in a microencapsulated matrix) with one week separating conditions. Fasting blood samples were collected during each visit; 30 minutes following a rest period and before placebo or supplement intake (Pre); 2 hours post intake (2 hr); one minute following the cessation of 30 minutes of exercise performed at 65% of maximal heart rate reserve (2.5 hr); 90 minutes following the cessation of exercise (4 hr). Heart rate (HR), systolic (SBP) and diastolic (DBP) blood pressure were recorded at all times. A time effect was noted for HR, SBP, and DBP (p < 0.05), with HR and SBP higher at 2.5 hr compared to Pre (due to exercise) and DBP lower at 2.5 hr compared to Pre. No interaction or condition effects were noted for EPI, NE, FFA, or glycerol (p > 0.05). However, a time effect was noted for all variables (p < 0.0001), with values higher than Pre at 2.5 hr for EPI and glycerol, at 2 hr and 2....Continue Reading

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Citations

Apr 25, 2012·Wiener klinische Wochenschrift·Muhammet Rasit SayinMustafa Aydin
Apr 12, 2016·Journal of Toxicology·Jayant DeshpandeVijaya Juturu
Sep 26, 2015·Seminars in Immunopathology·Andrei V Derbenev, Andrea Zsombok
Jun 18, 2016·Journal of Nutrition and Metabolism·Vijaya Juturu
May 14, 2016·British Journal of Pharmacology·Padmamalini BaskaranBaskaran Thyagarajan
May 19, 2016·Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Médicas E Biológicas·A S R HudsonS P Wanner
Jul 30, 2020·Current Diabetes Reports·Andrea Mendez-GutierrezGuillermo Sanchez-Delgado
Jun 30, 2019·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Cristian ScheauMonica Neagu

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Methods Mentioned

BETA
enzyme linked immunosorbent assay

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