Effect of paf-acether on isoprenaline-induced relaxation in isolated tracheal segments of rats and guinea pigs

European Journal of Pharmacology
N ChandR D Sofia

Abstract

Platelet activating factor (paf-acether) was found to contract rat and guinea pig tracheal segments. It does not cause down regulation of beta-adrenoceptor in guinea pig trachea. In addition, paf-contracted rat tracheal segments lose their ability to relax in response to isoprenaline.

References

Feb 27, 1987·Biochemical and Biophysical Research Communications·D K Agrawal, R G Townley
Jan 1, 1988·The Journal of Allergy and Clinical Immunology·C P Page
Jan 1, 1988·The Journal of Allergy and Clinical Immunology·P J Barnes
Jan 1, 1988·International Archives of Allergy and Applied Immunology·V LagenteB B Vargaftig
May 7, 1982·European Journal of Pharmacology·A PrancanB B Vargaftig

Citations

Jan 1, 1990·Pharmacology & Therapeutics·R G GoldieK M Lulich
May 1, 1991·Medicinal Research Reviews·P BraquetM Koltai
Jan 1, 1991·Research in Experimental Medicine. Zeitschrift Für Die Gesamte Experimentelle Medizin Einschliesslich Experimenteller Chirurgie·S B FelixW E Berdel

Related Concepts

Metazoa
Carboptic
Cavia porcellus
Novodrin
Inotropism
Muscle Relaxation Phase
Platelet Activating Factor
August Rats
Beta-adrenergic receptor
Trachea

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