Jun 1, 1989

Effect of pancreastatin on pancreatic exocrine secretion in vivo and in vitro

Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology
K MiyasakaK Kitani

Abstract

The effects of pancreastatin on pancreatic exocrine secretion were examined both in vivo and in vitro in rats. Pancreastatin inhibited pancreatic fluid and protein outputs stimulated by the exclusion of pancreatic juice from the intestine with the intraduodenal infusion of Trasylol but did not inhibit bicarbonate output stimulated by HCl in vivo in conscious rats. However, pancreastatin did not affect amylase release from dispersed acini or Ca concentration in acinar cells. Therefore, it is concluded that pancreastatin inhibits pancreatic exocrine secretion but the effect is indirect.

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Mentioned in this Paper

CHGA gene
Pancreatic Exocrine Secretion
August Rats
Trasylol
Amylase Measurement
Intestinal Wall Tissue
Pancreatic Juice
Amylases
Bicarbonate Measurement
Pancreatic Hormones

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