Effect of Personal Exposure to PM2.5 on Respiratory Health in a Mexican Panel of Patients with COPD

International Journal of Environmental Research and Public Health
Marlene Cortez-LugoAlbino Barraza-Villarreal

Abstract

Air pollution is a problem, especially in developing countries. We examined the association between personal exposure to particulate matter with an aerodynamic diameter less than 2.5 µm (PM2.5) on respiratory health in a group of adults with chronic obstructive pulmonary disease (COPD). All participants resided in Mexico City and during follow-up, personal exposure to PM2.5, respiratory symptoms, medications, and daily activity were registered daily. Peak expiratory flow (PEF) was measured twice daily, from February through December, 2000, in 29 adults with moderate, severe, and very severe COPD. PEF changes were estimated for each 10 µg/m³ increment of PM2.5, adjustment for severity of COPD, minimum temperature, and day of the sampling. For a 10-µg/m³ increase in the daily average of a two-day personal exposure to PM2.5, there was a significant 33% increase in cough (95% CI, range, 5-69%), and 23% in phlegm (95% CI, range, 2-54%), a reduction of the PEF average in the morning of -1.4 L/min. (95% CI , range, -2.8 to -0.04), and at night of -3.0 L/min (95% CI, range, -5.7 to -0.3), respectively. Exposure to PM2.5 was associated with reductions in PEF and increased respiratory symptoms in adults with COPD. The PEF reduction was o...Continue Reading

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Citations

Jun 2, 2017·International Journal of Biometeorology·Zhe MuQing-Yun Li
Mar 7, 2019·International Journal of Environmental Research and Public Health·Hanns MoshammerStefanie Peter
May 1, 2020·International Journal of Environmental Research and Public Health·Afua Asabea Amoabeng NtiJulius N Fobil
Dec 11, 2019·Biomolecules·Yadira Velasco-TorresCarlos Ramos
Feb 27, 2020·International Journal of Environmental Research and Public Health·Hone-Jay Chu, Muhammad Zeeshan Ali
Jan 6, 2019·International Journal of Environmental Research and Public Health·Chaicharn PothiratNittaya Phetsuk
Nov 30, 2019·Environmental Research·Yingmeng NiJieming Qu
Feb 6, 2021·The European Respiratory Journal·Dimitris EvangelopoulosBenjamin Barratt

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