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Effect of pharmacological agents on human keratinocyte mitosis in vitro. II. Inhibition by catecholamines

Journal of Cellular Physiology

Oct 1, 1975

R A Harper, B A Flaxman

Abstract

Catecholamines produce mitotic inhibition in primary cell cultures of human keratinocytes probably via a block in the G2 part of the cell cycle. Epinephrine produced significant mitotic inhibition (49%) at a concentration as low as 4.5 X 10(-10) M, while its analog, isoproterenol, produ...read more

Mentioned in this Paper

Amines
Primary Cell Culture
M Phase, Mitotic
Dopamine Measurement
Epinephrine Measurement
Norepinephrine Measurement
Serotonin Measurement
Metabolic Inhibition
Isoproterenol
Z-Max
18
Paper Details
References
  • References19
  • Citations12
12

Effect of pharmacological agents on human keratinocyte mitosis in vitro. II. Inhibition by catecholamines

Journal of Cellular Physiology

Oct 1, 1975

R A Harper, B A Flaxman

PMID: 410

DOI: 10.1002/jcp.1040860213

Abstract

Catecholamines produce mitotic inhibition in primary cell cultures of human keratinocytes probably via a block in the G2 part of the cell cycle. Epinephrine produced significant mitotic inhibition (49%) at a concentration as low as 4.5 X 10(-10) M, while its analog, isoproterenol, produ...read more

Mentioned in this Paper

Amines
Primary Cell Culture
M Phase, Mitotic
Dopamine Measurement
Epinephrine Measurement
Norepinephrine Measurement
Serotonin Measurement
Metabolic Inhibition
Isoproterenol
Z-Max
18

Related Papers

Paper Details
References
  • References19
  • Citations12
12
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