Effect of photorefractive keratectomy with mitomycin-C on corneal biomechanical features

Current Eye Research
Mohammad ZareHamed Esfandiari

Abstract

To evaluate corneal biomechanical properties and intraocular pressure (IOP) after photorefractive keratectomy (PRK) with or without mitomycin-C (MMC) 0.02% in myopic eyes. In this prospective, comparative interventional case series, 33 right eyes of 33 patients were included. Corneal hysteresis (CH), corneal resistance factor (CRF), Goldmann-correlated IOP (IOPg), and cornea-compensated IOP (IOPcc) were measured using ocular response analyzer (ORA) before and 3 months after PRK. IOP was determined using Goldmann applanation tonometry (GAT). The pre- and post-operative values were compared. Effects of ablation depth, optical zone (OZ) and duration of MMC application on corneal biomechanics were examined. Mean ablation depth was 56.6 ± 20.8 μm. Postoperatively, there was a significant reduction in corneal biomechanics and IOP readings by the GAT and ORA. Ablation depth was significantly associated with percentage change in CH (P = 0.021), CRF (P = 0.001), and IOP GAT (P < 0.001). However, the size of OZ and duration of MMC application did not have any correlation with these parameters. The percentage change in IOP GAT and IOPg but not IOPcc was significantly associated with percentage change in CH and CRF. The corneal biomechanic...Continue Reading

References

Apr 26, 2003·Investigative Ophthalmology & Visual Science·Tae-im KimMichael S Kook
Aug 27, 2003·Investigative Ophthalmology & Visual Science·Claude KaufmannMichael A Thiel
Apr 20, 2004·Journal of Cataract and Refractive Surgery·Dimitrios S SiganosCarlos Moedas
Aug 25, 2004·Investigative Ophthalmology & Visual Science·Tae-Im KimHungwon Tchah
Feb 22, 2005·Journal of Cataract and Refractive Surgery·Jun Liu, Cynthia J Roberts
Feb 22, 2005·Journal of Cataract and Refractive Surgery·David A Luce
Jul 9, 2005·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Helena SvedbergHelene Hamberg-Nyström
Feb 14, 2006·Journal of Cataract and Refractive Surgery·Dong H LeeJong G Kim
Oct 3, 2006·Journal of Cataract and Refractive Surgery·Madhavan S RajanJohn Marshall
Nov 7, 2006·Contact Lens & Anterior Eye : the Journal of the British Contact Lens Association·Sunil ShahSanjay Mantry
May 29, 2007·Journal of Cataract and Refractive Surgery·Laura de Benito-LlopisMaría Ortega
Jul 13, 2007·Ophthalmology·J Bradley RandlemanR Doyle Stulting
Jul 31, 2007·Journal of Cataract and Refractive Surgery·Dolores OrtizJorge L Alió
Sep 25, 2007·Acta Ophthalmologica·Caitriona Kirwan, Michael O'Keefe
Nov 14, 2008·Journal of Cataract and Refractive Surgery·Michael C ChenD Rex Hamilton

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Citations

May 27, 2014·Journal of Cataract and Refractive Surgery·David P Piñero, Natividad Alcón
Feb 25, 2015·Oman Journal of Ophthalmology·Hassan HashemiSoheila Asgari
Apr 27, 2017·Current Opinion in Ophthalmology·Meleha AhmadAnurag Shrivastava
Dec 2, 2020·International Journal of Environmental Research and Public Health·Gracia Castro-LunaHazem Alaskar-Alani

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