Effect of physical training on age-related reduction of GH secretion during exercise in normally cycling women

Maturitas
Vittorio CoiroPaolo Chiodera

Abstract

To evaluate whether prolonged physical activity (25 km/week running for 8 years) modifies GH decline. The GH response to maximal exercise on bicycle-ergometer was tested in younger (26-30 years) and older (42-46 years) healthy women. Each age group included 2 subgroups of 10 sedentary and 10 runners, which were compared. The workload was increased at 3 min intervals from time 0 until exhaustion. Subjects with a low maximal capacity (as established in a preliminary test) pedalled for 3-4 min against no workload at the beginning of the test, so that exercises lasted about 15 min in all individuals. At exhaustion, heart rate and systolic pressure were significantly higher in sedentary than in trained subjects, whereas V(O(2)max), blood glucose and plasma lactate levels were similar in all groups. Exercise induced similar GH responses in younger sedentary and exercise-trained subjects and in older exercise-trained subjects, with mean peak levels 7.5 times higher than baseline. In contrast, in older sedentary women peak GH level was only 4.4 times higher than baseline and was significantly lower than in the other groups. These data suggest that in women prolonged physical training exerts protective effects against age-dependent decl...Continue Reading

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Citations

Jul 20, 2014·Growth Hormone & IGF Research : Official Journal of the Growth Hormone Research Society and the International IGF Research Society·J JanukonytėT Laursen
Nov 3, 2015·The Tohoku Journal of Experimental Medicine·Masayuki OmotoNaoto Shiba
Sep 26, 2015·Climacteric : the Journal of the International Menopause Society·M Hagner-DerengowskaJ Budzyński
Jan 22, 2013·Maturitas·N MendozaUNKNOWN Spanish Menopause Society, EMAS
Nov 29, 2014·Rejuvenation Research·Nuria GaratacheaAlejandro Lucia
Jun 12, 2018·Frontiers in Endocrinology·Alexandre Rebelo-MarquesJoão Espregueira-Mendes
Aug 28, 2020·Frontiers in Nutrition·Diana Zukas AndreottiElisa Mitiko Kawamoto

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