Effect of physical training on bone adaptation in three zones of the rat tibia

Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research
S BourrinC Alexandre

Abstract

This study as been conducted to examine the effects of physical exercise on the bone trabecular network and the cellular adaptations in three different areas of a single bone, the tibia. Male Wistar rats (9 weeks old) were treadmill-trained for 0, 3, 4, or 5 weeks at 60% of their measured maximal O2 consumption (VO2max). Histomorphometric analysis of the proximal tibia of running and age-matched control groups was performed in the epiphyseal trabecular bone, in the primary spongiosa and in the secondary spongiosa. Dynamic and static bone cell activities and serum calcium and phosphorus levels were measured. VO2max increased significantly by 18.4% after 5 weeks of training. In the epiphysis, a 9% increase in bone volume, associated with more numerous trabeculae (8%) was detected the third week of training. In primary spongiosa a significant increase (6.7%) in newly formed trabeculae was found. In secondary spongiosa bone volume increased significantly by 26.2% the fifth week of exercise and was associated with thicker trabeculae. The number of osteoclast profiles was significantly depressed. Osteoid surfaces and bone formation rate increased significantly in weeks 3 to 5. Serum calcium levels were found to be significantly decre...Continue Reading

References

Jan 1, 1978·Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology·A Kiiskinen, E Heikkinen
Sep 1, 1978·Annals of Internal Medicine·J F AloiaK Ellis
Aug 1, 1992·Calcified Tissue International·S BourrinC Alexandre
Dec 1, 1992·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·L E Lanyon
Jan 1, 1990·Journal of Applied Physiology·D M RaabD P Thomas
Oct 1, 1989·Archives of Internal Medicine·B A MichelJ F Fries
Sep 1, 1989·Bone and Mineral·A Swissa-SivanS Samueloff
Apr 1, 1986·Calcified Tissue International·L E LanyonG Baust
Jan 1, 1988·Bone·D J Cavanaugh, C E Cann
Apr 1, 1988·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·R R ReckerS Hinders
Dec 1, 1987·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·A M ParfittR R Recker
Aug 1, 1987·Journal of Applied Physiology·D DesplanchesR Flandrois
Jun 1, 1986·Journal of Applied Physiology·J J MatsudaJ A Maynard
Oct 1, 1994·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Z PengH K Väänänen
May 1, 1994·Journal of Applied Physiology·S BourrinC Alexandre
Mar 1, 1994·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·C H SøgaardL Mosekilde
Sep 1, 1993·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·J K YehS Sprintz

❮ Previous
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Citations

Jul 28, 2005·Joint, Bone, Spine : Revue Du Rhumatisme·Bertrand LecoqChristian Marcelli
Oct 9, 1999·Mechanisms of Ageing and Development·M J DaviccoJ P Barlet
Jun 16, 2012·Journal of Biomedicine & Biotechnology·Joana ReisJosé Potes
Aug 2, 2003·BMC Cell Biology·Gary J Spencer, Paul G Genever
Nov 24, 2004·The Journal of Orthopaedic and Sports Physical Therapy·Ann E BarrBrian D Clark
Apr 26, 2000·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·P AmmannR Rizzoli
Apr 3, 2012·Calcified Tissue International·Nina HamannAnja Niehoff
Feb 26, 1998·Journal of Applied Physiology·K C WesterlindR T Turner
Aug 26, 1998·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·J IwamotoS Ichimura
Jun 28, 2005·Journal of Bone and Mineral Metabolism·Yoshinobu HagiharaHideshige Moriya
Sep 1, 2005·Journal of Bone and Mineral Metabolism·Terje SöötMati Pääsuke
Jan 24, 2007·American Journal of Physiology. Heart and Circulatory Physiology·Adam J ChiccoRussell L Moore
May 21, 2009·Sports Medicine·Amelia Guadalupe-GrauJose A L Calbet
Jan 10, 2001·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·T NotomiM Suzuki
Feb 24, 2005·Experimental Animals·Jun IwamotoYoshihiro Sato
Nov 11, 2003·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Toshiharu MoriToshitaka Nakamura
Dec 13, 2007·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·C M ModleskyG A Dudley
Sep 27, 2020·Life·Hugues PortierStéphane Pallu
Sep 8, 2000·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·J IwamotoJ F Aloia
Aug 18, 2004·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Zhenqiang YaoLaurence Vico
Aug 24, 1999·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·P A BaldockH A Morris
Jul 5, 2008·Journal of Bone and Mineral Metabolism·Tsang-Hai HuangRong-Sen Yang
Oct 31, 2006·Journal of Bone and Mineral Metabolism·Gaële DucherDaniel Courteix
Feb 6, 2002·Medicine and Science in Sports and Exercise·Craig S DuncanRobert Howman-Giles
Jul 20, 2004·Journal of Applied Physiology·J M WelchC H Turner
Aug 10, 2000·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·S BourrinR Rizzoli
Apr 4, 2021·Experimental & Molecular Medicine·Sun Young LeeJe-Hwang Ryu
Jun 9, 2001·Biochemical and Biophysical Research Communications·C GranetM H Lafage-Proust
Oct 13, 2021·JBJS Reviews·Sasha CarsenPaul E Beaulé
Feb 2, 2010·Journal of Biomechanics·C FriasA T Marques

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