Effect of platelet-rich plasma on bone regeneration in dentistry: a systematic review

Clinical Oral Implants Research
Adelina S PlachokovaNico H J Creugers

Abstract

To review systematically the reported effects of platelet-rich plasma (PRP) on bone regeneration. Up to June 2006, MEDLINE and Cochrane databases were explored with different combinations of three search terms: 'PRP', 'bone regeneration', 'dentistry' and their synonyms. human controlled clinical trials designed to treat maxillofacial bony defects with application of PRP (test) or without PRP (control), including at least five patients with a follow-up period of more than 3 months and using clinical assessment, radiography, histology and/or histomorphometry for evaluation. Literature search, selection of eligible articles and data extraction were carried out independently by two readers. The literature search revealed 108 references, of which 17 were selected for further analysis. Finally, nine articles fulfilling the inclusion criteria were selected for systematically review. Owing the substantial heterogeneity of the studies it was not possible to analyze the data statistically. An attempt was made to compare results from studies that used similar outcome measures by calculating and adding confidence intervals to the data presented in the original papers. Differences in treatment effects for periodontal defects in terms of cli...Continue Reading

References

Apr 1, 1989·Statistics in Medicine·G A ColditzF Mosteller
Mar 1, 1997·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·D M GalenD Buchbinder
Jun 25, 1998·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·R E MarxK R Georgeff
Aug 24, 1999·Journal of Child Neurology·O A TorresK Hyland
Jul 7, 2001·BMJ : British Medical Journal·P JüniM Egger
Nov 7, 2002·International Journal of Oral and Maxillofacial Surgery·H Schilephake
Nov 28, 2002·Journal of Dental Research·R MontenegroM Tonetti
May 10, 2003·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·Emmanuel SofferFani Anagnostou
Sep 13, 2003·Clinical Oral Implants Research·Norbert JakseChristof Pertl
Apr 16, 2004·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Earl G Freymiller, Tara L Aghaloo
Apr 16, 2004·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Robert E Marx
May 4, 2004·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Tomoki OyamaFumiaki Shimizu
Mar 8, 2005·The Journal of Craniofacial Surgery·James D Kassolis, Mark A Reynolds
Jun 10, 2005·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Gilberto SammartinoPier Paolo Claudio
May 18, 2006·The Journal of Oral Implantology·Eduardo A Anitua
Jun 13, 2006·Implant Dentistry·Lakshmi Boyapati, Hom-Lay Wang

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Citations

May 31, 2012·Archives of Orthopaedic and Trauma Surgery·A M EweidaR E Horch
May 24, 2013·Journal of Artificial Organs : the Official Journal of the Japanese Society for Artificial Organs·Hirotsugu HondaAkira Myoui
Dec 28, 2011·Journal of Materials Science. Materials in Medicine·Cheng XieYi-Min Zhao
Jan 19, 2013·BioDrugs : Clinical Immunotherapeutics, Biopharmaceuticals and Gene Therapy·Eduardo AnituaGorka Orive
Feb 12, 2013·Journal of Cranio-maxillo-facial Surgery : Official Publication of the European Association for Cranio-Maxillo-Facial Surgery·Prisana PripatnanontKingkaew Phurisat
Oct 29, 2009·Tissue Engineering. Part B, Reviews·Fa-Ming Chen, Yan Jin
Jan 7, 2010·Tissue Engineering. Part C, Methods·Sebastian SauerbierRalf Gutwald
Sep 8, 2011·Tissue Engineering. Part C, Methods·Karl-Heinz Schuckert, Magdalena Osadnik
Mar 3, 2012·Implant Dentistry·Jaime S Guerrero, Badr A Al-Jandan
Aug 26, 2010·The Journal of Oral Implantology·Ricardo V GarciaJamil A Shibli
Apr 19, 2012·Journal of Periodontology·Satheesh ElangovanVeerasathpurush Allareddy
Nov 27, 2009·Vojnosanitetski pregled. Military-medical and pharmaceutical review·Zoran LazićBranko Mihajlović
Oct 26, 2010·Oral and Maxillofacial Surgery·Silvio TaschieriMassimo Del Fabbro
Aug 12, 2014·The Journal of Oral Implantology·Vicki L DavisJames L Rutkowski
Aug 8, 2014·Journal of Periodontology·Maria J H NagataEdilson Ervolino
Jun 15, 2013·Immunity & Ageing : I & a·Antonino AlbaneseGiuseppina Campisi
Dec 10, 2013·Medicina oral, patología oral y cirugía bucal·C Barona-DoradoJ-M Martínez-González
Jul 23, 2014·Journal of Investigative and Clinical Dentistry·Saurav PandaMassimo Del Fabbro
Dec 4, 2015·Journal of Endodontics·Massimo Del FabbroRoberto L Weinstein
Jan 29, 2013·Journal of Cranio-maxillo-facial Surgery : Official Publication of the European Association for Cranio-Maxillo-Facial Surgery·Guilherme de Marco AntonelloCarmen Helena Jacques Lemes
Jun 10, 2014·Clinical Implant Dentistry and Related Research·Mohammed A AlfarsiSaso Ivanovski
Oct 17, 2012·The Journal of Evidence-based Dental Practice·Mark A Reynolds, Mary E Aichelmann-Reidy
May 19, 2012·Journal of Endodontics·Massimo Del FabbroSilvio Taschieri
Dec 6, 2011·Biotechnology Advances·Fa-Ming ChenSongtao Shi
Jan 19, 2016·International Journal of Oral and Maxillofacial Surgery·C A A LemosE P Pellizzer
Aug 30, 2011·Journal of Cranio-maxillo-facial Surgery : Official Publication of the European Association for Cranio-Maxillo-Facial Surgery·Philipp MetzlerKarl Andreas Schlegel
Jul 19, 2011·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Marcos Martins CuriMarcelo Oliveira dos Santos
May 24, 2011·International Journal of Oral and Maxillofacial Surgery·M Del FabbroS Taschieri
Oct 27, 2010·Journal of Controlled Release : Official Journal of the Controlled Release Society·Fa-Ming ChenMin Zhang
May 25, 2010·Biomaterials·Fa-Ming ChenZhi-Fen Wu
May 11, 2010·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·Shengyun Huang, Zuolin Wang
Jan 28, 2010·Dental Clinics of North America·Mark A ReynoldsGrishondra L Branch-Mays
May 16, 2009·International Journal of Oral and Maxillofacial Surgery·A S PlachokovaJ A Jansen

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