Effect of Pod e-Cigarettes vs Cigarettes on Carcinogen Exposure Among African American and Latinx Smokers: A Randomized Clinical Trial

JAMA Network Open
Kim PulversJasjit S Ahluwalia

Abstract

Fourth-generation nicotine salt pod system (NSPS) electronic cigarettes (e-cigarettes) are the leading class of e-cigarettes. They contain high nicotine concentrations, which may facilitate switching among smokers, but could also lead to increased exposure to nicotine and biomarkers of potential harm. African American and Latinx smokers experience significant tobacco-related health disparities. The potential of NSPS e-cigarettes to reduce smoking-related harm among these groups is unknown. To compare the harm reduction potential of NSPS e-cigarette vs combustible cigarettes. This unblinded randomized clinical trial compared 6 weeks of e-cigarette use vs cigarettes as usual from to 2018 to 2019 among smokers in the San Diego, California, and Kansas City, Missouri, areas. Participants included African American and Latinx adult combustible cigarette smokers who smoked at least 5 cigarettes/d on at least 25 of the past 30 days for at least 6 months and were interested in switching to e-cigarettes. Data were analyzed from September 18, 2019, to September 4, 2020. 6 weeks of e-cigarette use in a choice of pod flavors (5% nicotine) along with brief education, training, and action planning to completely switch to e-cigarettes from comb...Continue Reading

Associated Clinical Trials

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Citations

Apr 30, 2021·The Cochrane Database of Systematic Reviews·Jamie Hartmann-BoycePeter Hajek
Apr 11, 2021·Nicotine & Tobacco Research : Official Journal of the Society for Research on Nicotine and Tobacco·Michael J ArnoldKim Pulvers
Feb 3, 2021·Panminerva Medica·Elio VenturiniFrancesco Giallauria
Aug 15, 2021·Tobacco Control·Brian J MillerBoris D Lushniak
Aug 20, 2021·American Journal of Public Health·David J K BalfourRobert West
Sep 15, 2021·The Cochrane Database of Systematic Reviews·Jamie Hartmann-BoycePeter Hajek
Nov 5, 2021·Tobacco Control·Marzena HilerElena V Mishina
Oct 21, 2021·Nicotine & Tobacco Research : Official Journal of the Society for Research on Nicotine and Tobacco·Kolawole S OkuyemiAnne M Joseph

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Methods Mentioned

BETA
pharmacotherapy

Software Mentioned

R
REDCap
R Project for Statistical Computing
Excel

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