Effect of polymorphisms in candidate genes on reproduction traits in Finnish pig populations

Journal of Animal Science
Anu SironenJ Vilkki

Abstract

Reproduction traits play an important role in economically viable piglet production and are closely related to the quality and length of the productive life of the sow. A increased removal rate of young sows is undesirable not only because of the associated financial penalties incurred, but also because of ethical concerns. Candidate genes and gene pathways have been identified for fertility in model species, and recent studies have provided evidence that polymorphisms within these genes are associated with reproduction traits in American Yorkshire/Large White and Landrace populations. In this study we evaluated the impact of single polymorphisms (n = 7) in 7 candidate genes on reproductive efficiency in Finnish Yorkshire (n = 280) and Landrace (n = 271) populations: IGFBP1, IGFBP2, IGFBP3, IGFBP5, CPTIA (carnitine O-palmitoyltransferase I), COX2 (PG-endoperoxide synthase 2, also known as cyclooxygenase-2), and SLC22A5 [organic cation/carnitine transporter 2 (solute carrier family member I), OCTN2]. In the Finnish Yorkshire population, only 4 of the analyzed markers were polymorphic. Significant effects on farrowing time were detected from the Yorkshire data, with polymorphisms within the genes CPT1A [a (allele substitution eff...Continue Reading

References

Jun 1, 1997·Clinical Endocrinology·J A de BoerE A van der Veen
Aug 31, 2000·Annual Review of Biochemistry·W L SmithR M Garavito
Apr 9, 2002·Preventive Veterinary Medicine·Thomaz LuciaJairo E M Matheus
Dec 3, 2003·Human Reproduction·J-C HuangK K Wu
Sep 30, 2005·Journal of Animal Breeding and Genetics = Zeitschrift Für Tierzüchtung Und Züchtungsbiologie·M J EhlersK J Stalder
Apr 4, 2006·Journal of Animal Science·T Serenius, K J Stalder
Nov 14, 2007·Journal of Animal Science·L EngblomK Andersson
Sep 6, 2008·Prostaglandins, Leukotrienes, and Essential Fatty Acids·Pranab Lal Pakrasi, Anil K Jain
Apr 11, 2009·Journal of Animal Science·B E MoteM F Rothschild

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Citations

Jul 15, 2011·Reproduction in Domestic Animals = Zuchthygiene·K KaewmalaK Schellander
Sep 5, 2015·Journal of Animal Science and Technology·Sombat PrasongsookSornthep Tumwasorn
Mar 29, 2016·Animal Science Journal = Nihon Chikusan Gakkaihō·Shuji SatoKeiichi Suzuki
May 1, 2018·Frontiers in Endocrinology·Marion Spitschak, Andreas Hoeflich
Dec 5, 2019·Acta Veterinaria Scandinavica·Nina Hårdnes TremoenDag Inge Våge
Jul 27, 2015·Molecular Biology Reports·Moshen JafarikiaMarie-France Palin

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