Effect of porcine somatotropin administration in young pigs during the growth phase from 10 to 25 kilograms

Journal of Animal Science
R J HarrellD E Bauman

Abstract

We conducted two experiments to determine the efficacy of exogenous porcine somatotropin (pST) on enhancing performance during an early phase of growth (10 kg initial BW) when pigs are already growing efficiently and have high rates of lean deposition and low rates of lipid deposition. In Exp. 1, performance was measured on 45 barrows that received one of five daily doses (0, 50, 100, 150 and 200 microg/kg BW) of recombinant pST. In Exp. 2, 27 barrows were used in a slaughter-balance study in which two groups received daily either buffer (control) or 120 microg/kg BW of pST and the third group was slaughtered for initial body composition. In both experiments, pigs received daily i.m. injections of their respective dose for 20 d. The diet was fed for ad libitum consumption and calculated to contain 3.5 Mcal DE/kg, 22.3% CP, and 1.5% lysine. Administration of pST failed to alter overall growth rate or efficiency of gain in either experiment. However, in Exp. 2 pigs treated with pST had increased deposition rates of protein and water but reduced lipid deposition rates. Furthermore, pST treatment resulted in characteristic reductions in plasma urea nitrogen and elevations in glucose and NEFA. Plasma concentrations of insulin and IG...Continue Reading

Citations

Jan 23, 1999·The Journal of Nutrition·Y WangP A Schoknecht
Apr 16, 1999·Journal of Pediatric Gastroenterology and Nutrition·W E Ward, S A Atkinson
Oct 22, 2002·American Journal of Physiology. Endocrinology and Metabolism·Jill A BushTeresa A Davis
Aug 7, 2008·American Journal of Physiology. Endocrinology and Metabolism·Fiona A WilsonTeresa A Davis
May 8, 2008·American Journal of Physiology. Endocrinology and Metabolism·Fiona A WilsonTeresa A Davis
Jul 23, 1998·Physiological Reviews·T D Etherton, D E Bauman
Oct 8, 2009·Molecular Therapy : the Journal of the American Society of Gene Therapy·Amir S KhanMarta L Fiorotto
Mar 21, 1998·The Journal of Nutrition·A W BellR J Harrell
Feb 20, 2007·Growth Hormone & IGF Research : Official Journal of the Growth Hormone Research Society and the International IGF Research Society·M E López-OlivaE Muñoz-Martínez
May 15, 2007·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·M E López-OlivaE Muñoz-Martínez

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