Effect of post crosslinking haze on the repeatability of Scheimpflug-based and slit-scanning imaging devices

Indian Journal of Ophthalmology
Rohit ShettyChaitra Jayadev

Abstract

The aim of this study was to analyze the effect of postcollagen crosslinking (CXL) haze on the measurement and repeatability of pachymetry and mean keratometry (Km) of four corneal topographers. Sixty eyes of sixty patients with progressive keratoconus who had undergone accelerated CXL (ACXL) underwent imaging with a scanning slit imaging device (Orbscan II) and three Scheimpflug imaging devices (Pentacam HR, Sirius, and Galilei). Post-ACXL haze was measured using the densitometry software on the Pentacam HR. Readings of the thinnest corneal thickness (TCT) and Km from three scans of each device were analyzed. Effect of haze on the repeatability of TCT and Km measurements was evaluated using regression models. Repeatability was assessed by coefficient of variation. Corneal densitometry in different zones affected the repeatability of TCT measurement of Orbscan (P < 0.05) significantly but not the repeatability of TCT with Pentacam HR and Sirius (P = 0.03 and 0.05, respectively). Km values were affected by haze when measured with the Pentacam HR (P < 0.05). The repeatability of Km readings for all devices was unaffected by haze. In the anterior 0-2 mm and 2-6 mm zone, TCT (P = 0.43 and 0.45, respectively), Km values (P = 0.4 and...Continue Reading

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Citations

Jun 12, 2019·Clinical & Experimental Optometry : Journal of the Australian Optometrical Association·Ahmed S BardanMayank A Nanavaty
Mar 28, 2018·International Ophthalmology·Myriam BöhmThomas Kohnen

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Methods Mentioned

BETA
confocal microscopy

Software Mentioned

Pentacam
Stata
Orbscan

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