Effect of preoperative erythromycin or dexamethasone/vitamin C on postoperative abomasal emptying rate in dairy cows undergoing surgical correction of abomasal volvulus

Veterinary Surgery : VS
Thomas WittekManfred Fürll

Abstract

To determine the effects of preoperative erythromycin or combined dexamethasone/vitamin C treatment on postoperative abomasal emptying rate in cows undergoing surgical correction of abomasal volvulus (AV). Prospective, controlled, clinical study using a convenience sample. Lactating Holstein-Friesian cows (n=45) with AV were alternately assigned to 3 groups (n=15): group C: untreated (control); group E: erythromycin (10 mg/kg intramuscularly [IM]); group D: dexamethasone (0.02 mg/kg intravenously [IV]) and vitamin C (10 mg/kg IV). Drugs were administered 1 hour before surgical correction of AV. D-xylose solution (50%, 0.5 g/kg body weight) was injected into the abomasal lumen during surgery. Jugular venous blood samples for determination of serum d-xylose concentration were periodically obtained. Time to maximal serum D-xylose concentration (T(max-model)) was pharmacokinetically determined. Abomasal emptying rate was significantly (P<0.05) faster in group E (T(max-model)=182+/-69 min; mean+/-SD) than in group C cows (T(max-model)=237+/-64 min). Abomasal emptying rate was similar in group D (T(max-model)=196+/-47 min) and group C. Both treatments improved postoperative milk yield within 1 day after surgery. Preoperative injectio...Continue Reading

References

Aug 1, 1978·The American Journal of Digestive Diseases·L BuenoY Ruckebusch
Jun 1, 1994·Digestive Diseases and Sciences·J J CullenK A Kelly
Oct 1, 1994·The British Journal of Surgery·M A Pilot
Apr 16, 1998·Anesthesia and Analgesia·R A Steinbrook
Nov 7, 1998·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·T GeishauserM Schemann
Apr 13, 2005·American Journal of Veterinary Research·Tessa S MarshallThomas Wittek
Apr 13, 2005·American Journal of Veterinary Research·Thomas Wittek, Peter D Constable
Jul 29, 2005·Journal of the American Veterinary Medical Association·Thomas WittekDawn E Morin
Nov 16, 2006·Journal of Veterinary Science·Jae-il LeeMyung-cheol Kim

❮ Previous
Next ❯

Citations

Apr 2, 2009·American Journal of Veterinary Research·Gholam-Reza AfshariPeter D Constable
Mar 1, 2012·The Veterinary Clinics of North America. Food Animal Practice·Peter D ConstableThomas Wittek
Nov 10, 2011·Journal of Veterinary Pharmacology and Therapeutics·M FazeliM Ghane
May 13, 2008·The Veterinary Clinics of North America. Food Animal Practice·Andrew J Niehaus
Sep 12, 2016·The Veterinary Clinics of North America. Food Animal Practice·Andrew J Niehaus
May 4, 2017·Tierärztliche Praxis. Ausgabe G, Grosstiere/Nutztiere·Marlene Sickinger

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.