Effect of prior glaucoma surgery on intraocular pressure immediately after anti-vascular endothelial growth factor injection

Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie
Jocelyn LamJoanne C Wen

Abstract

To characterize how prior incisional glaucoma surgery affects the intraocular pressure (IOP) elevation immediately following intravitreal anti-VEGF injections (IVI). Single institution, experimental study. Patients with a history of incisional glaucoma surgery who were receiving anti-VEGF injections were recruited as well as control eyes. Pre- and post-injection IOP measurements were compared as well as time to recovery to within 5 and 10 mmHg of baseline IOP. Ten eyes with a history of glaucoma surgery and 29 control eyes receiving anti-VEGF injections were included. The most common indication for intravitreal anti-VEGF injection was proliferative diabetic retinopathy in both surgical and control eyes (50% vs 45%, p = 1.00). Post-injection IOP was significantly decreased compared to baseline IOP after anti-VEGF injection in surgical versus control eyes (26.5 ± 8.9 mmHg vs 44.2 ± 8.5 mmHg, respectively, p < 0.001). The mean change in IOP following intravitreal anti-VEGF injection was lower in surgical eyes (10.7 ± 6.6 mmHg vs 28.6 ± 8.3 mmHg, p < 0.001). The mean time for the IOP to return to within 10 mmHg of pre-injection IOP was less in surgical eyes (5.2 ± 4.1 min vs 13.3 ± 7.6 min, p = 0.002). Eyes with prior incisional gl...Continue Reading

References

Nov 21, 2007·Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie·Hussein HollandsJeffery Gale
Nov 28, 2007·Retina·Iryna A FalkensteinWilliam R Freeman
Dec 17, 2009·Journal of Glaucoma·Maurizio GismondiPaolo Brusini
Aug 24, 2012·Investigative Ophthalmology & Visual Science·Jose M Martinez-de-la-CasaJulián Garcia-Feijoo
Apr 8, 2014·European Journal of Ophthalmology·Pablo Carnota-MéndezJosé Antonio Saavedra-Pazos
Mar 17, 2017·JAMA Ophthalmology·Brennan D EadieFrederick S Mikelberg
Jun 16, 2017·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Masoud SoheilianSeyed Aliasghar Mosavi
Apr 15, 2018·The British Journal of Ophthalmology·Pouya AlaghbandKin Sheng Lim
Nov 24, 2018·Scientific Reports·Takeshi IwaseHiroko Terasaki

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Citations

Mar 20, 2021·Current Ophthalmology Reports·Ronaldo Nuesi, Swarup S Swaminathan

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