Effect of Propolis on Experimental Cutaneous Wound Healing in Dogs

Veterinary Medicine International
Ashraf M Abu-Seida

Abstract

This study evaluates clinically the effect of propolis paste on healing of cutaneous wound in dogs. Under general anesthesia and complete aseptic conditions, two full thickness skin wounds (3 cm diameter) were created in each side of the chest in five dogs, one dorsal and one ventral, with 10 cm between them. These wounds were randomly allocated into two groups, control group (10 wounds) and propolis group (10 wounds). Both groups were represented in each dog. The wounds were cleaned with normal saline solution and dressed with macrogol ointment in control group and propolis paste in propolis group, twice daily till complete wound healing. Measurement of the wound area (cm(2)) was monitored planimetrically at 0, 7, 14, 21, 28, and 35 days after injury. The data were analyzed statistically. The results revealed a significant reduction in the wound surface area in the propolis group after 14 and 21 days compared to control group. The wound reepithelization, contraction, and total wound healing were faster in propolis group than in control group during five weeks of study. In conclusion, propolis paste has a positive impact on cutaneous wound healing and it may be suggested for treating various types of wounds in animals.

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Citations

Dec 22, 2017·Antibiotics·Soumya GhoshNaowarat Cheeptham
Apr 4, 2019·Journal of Medicinal Food·Mitzzy F Medellín-LunaAlberto R Cervantes-Villagrana
Mar 28, 2019·Journal of Liposome Research·Ayşegül Aylin AytekinÖzgen Özer
Dec 19, 2019·Frontiers in Veterinary Science·Mauricio Alcântara KalilRicardo Wagner Portela
Jul 14, 2017·Frontiers in Pharmacology·Laura CornaraBruno Burlando
Mar 22, 2021·Preventive Veterinary Medicine·Blayra Maldonado-CabreraAna Sanches-Silva
Apr 4, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Batoryna OlgierdMorawiec Emilia
Apr 19, 2018·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·Vahid Reza AskariHassan Rakhshandeh

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