Apr 1, 1979

Effect of propranolol on total exchangeable body potassium and total exchangeable body sodium in essential hypertension

Scandinavian Journal of Clinical and Laboratory Investigation
G PedersenE B Pedersen


Total exchangeable body potassium (KE) was determined in fifteen patients with essential hypertension, and total exchangeable body sodium (NaE) in ten, before and after propranolol administration for 2-3 months. Blood pressure was reduced; serum potassium increased, but KE was unchanged. Serum sodium and NaE were unaffected during therapy. It is concluded that the increase in serum potassium during propranolol treatment could not be attributed to potassium retention, but is possibly due to a displacement from the intra- to the extracellular fluid compartment. The antihypertensive effect of propranolol could not be related to changes in NaE.

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  • Citations17


Mentioned in this Paper

Extracellular Fluid
Serum Potassium Measurement
Essential Hypertension
Hypertensive Disease
Antihypertensive Agents
Anatomical Compartments
Blood Pressure

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