PMID: 490290Aug 1, 1979Paper

Effect of proximal gastric vagotomy and truncal vagotomy and pyloroplasty on gastric functions and growth in puppies after massive small bowel resection

Journal of Pediatric Surgery
S A WolfR R Dozois

Abstract

The effects of truncal vagotomy and pyloroplasty and proximal gastric vagotomy on gastric acid hypersecretion, hypergastrinemia, and growth after massive bowel resection were studied in beagle puppies. In puppies with 80% enterectomy, neither type of vagotomy alters significantly the postprandial hypersecretion of acid from the Heidenhain pouch or the concentration of serum gastrin. Proximal gastric vagotomy tended to decrease the hypersecretion more than did truncal vagotomy. In beagle puppies undergoing 70% small bowel resection, growth was significantly decreased but survival was not impaired. Neither proximal gastric vagotomy nor truncal vagotomy and pyloroplasty reversed completely the impaired growth produced by massive resection. Proximal gastric vagotomy caused a small improvements in growth, while truncal vagotomy and pyloroplasty resulted in a slight decrease in growth. It remains possible that proximal gastric vagotomy could be of value in the management of growing infants with hypersecretion of acid due to short bowel syndrome.

References

Jun 1, 1976·Journal of Pediatric Surgery·J M ScullyD L Dudgeon
Oct 1, 1969·Gut·C W WindsorD A Woodward
Mar 1, 1971·American Journal of Surgery·J D Burrington
Jan 25, 2013·Journal of Pediatric Gastroenterology and Nutrition·Sarah L AlmondAntonino Morabito

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Citations

Jun 23, 2004·Prostaglandins, Leukotrienes, and Essential Fatty Acids·Adnan AslanMustafa Melikoglu
Jul 1, 1985·The Journal of Surgical Research·J S Thompson
Jun 12, 2010·Journal of Vascular and Interventional Radiology : JVIR·Charles Y KimTony P Smith
Aug 21, 2008·Gastroenterology·Wim J E P LammersJan A J Schuurkes
Nov 1, 1994·Journal of Investigative Surgery : the Official Journal of the Academy of Surgical Research·J S Thompson, R F Harty
Jan 1, 1987·Annales Françaises D'anesthèsie Et De Rèanimation·Y MalledantC Saint-Marc

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