PMID: 43055Jan 1, 1979

Effect of psychotropic drugs on somatosensory evoked cortical potentials

Acta biologica et medica Germanica
K Lehmann, J Schmidt

Abstract

The effects of some typical clinically tested psychotropic drugs were studied in acute experiments on awake rats. Potentials in somatosensory cortex were evoked by peripheral stimulation. Haloperidol, diazepam, medazepam, desipramin and a new substance, the MPP-sulton, caused significant modification in latency and amplitude of some components of the potentials. Between the effects of psychotropic drugs exist differences which, in turn, were clearly distinguishable from the modification of these evoked responses by unspecific narcotic effects of hexobarbital.

Related Concepts

ratio-Desipramine
Assay OF Haloperidol
Anti-Anxiety Effect
Evipan
Medazepam
Medazepam AWD
MPP-sulton
Piperidines
Haloperidol
Structure of Cortex of Kidney

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