Abstract
The antiobesity and antihyperlipidaemic effects of pu-erh tea in rats with high fat diet (HFD)-induced obesity were investigated. Male Sprague-Dawley rats were randomly divided into five groups and fed varying diets for an 8-week period: control diet, HFD, and HFD supplemented with low, moderate or high doses of pu-erh tea extract (0.5 g, 2 g and 4 g/kg BW/day, respectively). Pu-erh tea significantly reduced the total body weight and the weight of various adipose pads. Pu-erh tea administration also significantly lowered plasma total cholesterol, triglyceride concentrations and low-density lipoprotein-cholesterol levels in rats with HFD-induced obesity, but did not affect high-density lipoprotein-cholesterol levels. Moreover, pu-erh tea significantly increased lipoprotein lipase, hepatic lipase and hormone-sensitive lipase activities in epididymal fat tissue in rats with HFD-induced obesity. Analysis of real-time reverse transcription-polymerase chain reaction results indicated that pu-erh tea significantly enhanced mRNA levels of hormone-sensitive lipase in rats with HFD-induced obesity. These results suggest that pu-erh tea attenuated visceral fat accumulation and improved hyperlipidemia in a rat model of HFD-induced obesity.
References
Sep 1, 1976·Physiology & Behavior·A Sclafani, D Springer
Apr 29, 2000·Journal of Clinical Epidemiology·F PaccaudP Bovet
Jun 1, 2000·The American Journal of Psychiatry·M J DevlinG T Wilson
Jun 6, 2000·The American Journal of Clinical Nutrition·H Mukhtar, N Ahmad
Oct 4, 2000·The Journal of Nutrition·C S Yang, J M Landau
Nov 18, 2000·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·J Y KimJ O Holloszy
Feb 15, 2001·Archives of Internal Medicine·T F Whayne, J C Zielke
Jul 18, 2001·Circulation·P Libby
Jan 18, 2002·The Journal of Biological Chemistry·Osnat Ben-ZeevMark H Doolittle
Dec 20, 2002·Obesity Research·Ken Fujioka
Dec 31, 2002·JAMA : the Journal of the American Medical Association·Ali H MokdadJames S Marks
Jul 12, 2003·Obesity Research·Constance FarleyTimothy J Kowalski
Jan 17, 2004·The Biochemical Journal·Stephen J Yeaman
Dec 23, 2004·Journal of Agricultural and Food Chemistry·Pin-Der DuhLee-Wen Chang
Jan 5, 2005·BioFactors·Ichiro Tokimitsu
Jan 20, 2005·Journal of Agricultural and Food Chemistry·Kuan-Li KuoJen-Kun Lin
Nov 16, 2005·Journal of the American College of Cardiology·Benjamin J AnsellGregg C Fonarow
Mar 21, 2007·Chemico-biological Interactions·Hyun-Seuk MoonChong-Su Cho
Sep 18, 2007·Journal of Lipid Research·G M Dallinga-ThieA van Tol
Jun 24, 2008·Phytotherapy Research : PTR·Hiroyuki Fujita, Tomohide Yamagami
Oct 31, 2008·Talanta·Yuegang ZuoYiwei Deng
Citations
Nov 16, 2010·Lipids in Health and Disease·Weihong LiShucun Qin
Jul 28, 2012·International Journal of Molecular Sciences·Yang XuWei Shi
Oct 28, 2015·Evidence-based Complementary and Alternative Medicine : ECAM·Jing-Na DengJing-Yan Han
Feb 7, 2015·PloS One·YiHong DingBin Liang
Jun 9, 2016·European Journal of Nutrition·Sumin WangJun Sheng
Oct 21, 2016·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Ru-Yue XiaoBin Liang
Oct 19, 2019·Biological Trace Element Research·Fen LiBin Yang
Apr 18, 2012·Phytotherapy Research : PTR·Yasuyuki OiKazunaga Yazawa
Oct 3, 2012·Phytotherapy Research : PTR·Zhen-Hui CaoQiu-Ye Lin
Jun 4, 2015·Electrophoresis·Zhonghua LiuGuoan Luo
Dec 18, 2015·Journal of the Science of Food and Agriculture·Jian LiuJia-Shun Gong
May 18, 2016·Food & Function·Ping XuYuefei Wang
Oct 11, 2016·Food & Function·Min-Hsiung PanChi-Tang Ho
Feb 7, 2017·Food & Function·Wen-Yi HuHe Sun
Jan 31, 2017·The British Journal of Nutrition·Dae-Bang SeoSung-Joon Lee
Jan 6, 2019·Applied Microbiology and Biotechnology·Yun XiaYunhong Kong
Dec 24, 2018·Nutrients·Phiwayinkosi V DludlaSithandiwe E Mazibuko-Mbeje
Sep 14, 2018·Oxidative Medicine and Cellular Longevity·Yihui XiaoZuyi Yuan
Jul 6, 2019·European Journal of Nutrition·Enkai WuJiashun Gong
Apr 6, 2017·Journal of Zhejiang University. Science. B·Guo-Qing HeGuo-Hua Zhang
Jan 10, 2018·Journal of the American College of Nutrition·E Paul CherniackHeather F Lee
Nov 2, 2019·Nature Communications·Fengjie HuangWei Jia
Feb 23, 2020·Experimental Gerontology·Jaciara Neves SousaSérgio Henrique Sousa Santos
Jul 9, 2021·Frontiers in Pharmacology·Qijing FanXiaoju Zou
Jun 18, 2021·Food Science & Nutrition·Qian-Qian MaoHua-Bin Li
Apr 10, 2012·Journal of Agricultural and Food Chemistry·Shi-Jun YanWen-Sheng Zhang
Jul 31, 2020·Journal of Ethnopharmacology·Pei-Rong LinJason T C Tzen
Sep 11, 2012·Journal of Agricultural and Food Chemistry·Wan-hong DuXiao-Qing Zou