Effect of pu-erh tea on body fat and lipid profiles in rats with diet-induced obesity

Phytotherapy Research : PTR
Zhen-Hui CaoChang-Rong Ge

Abstract

The antiobesity and antihyperlipidaemic effects of pu-erh tea in rats with high fat diet (HFD)-induced obesity were investigated. Male Sprague-Dawley rats were randomly divided into five groups and fed varying diets for an 8-week period: control diet, HFD, and HFD supplemented with low, moderate or high doses of pu-erh tea extract (0.5 g, 2 g and 4 g/kg BW/day, respectively). Pu-erh tea significantly reduced the total body weight and the weight of various adipose pads. Pu-erh tea administration also significantly lowered plasma total cholesterol, triglyceride concentrations and low-density lipoprotein-cholesterol levels in rats with HFD-induced obesity, but did not affect high-density lipoprotein-cholesterol levels. Moreover, pu-erh tea significantly increased lipoprotein lipase, hepatic lipase and hormone-sensitive lipase activities in epididymal fat tissue in rats with HFD-induced obesity. Analysis of real-time reverse transcription-polymerase chain reaction results indicated that pu-erh tea significantly enhanced mRNA levels of hormone-sensitive lipase in rats with HFD-induced obesity. These results suggest that pu-erh tea attenuated visceral fat accumulation and improved hyperlipidemia in a rat model of HFD-induced obesity.

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Citations

Oct 28, 2015·Evidence-based Complementary and Alternative Medicine : ECAM·Jing-Na DengJing-Yan Han
Oct 21, 2016·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Ru-Yue XiaoBin Liang
Apr 18, 2012·Phytotherapy Research : PTR·Yasuyuki OiKazunaga Yazawa
Dec 18, 2015·Journal of the Science of Food and Agriculture·Jian LiuJia-Shun Gong
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Jan 10, 2018·Journal of the American College of Nutrition·E Paul CherniackHeather F Lee
Feb 23, 2020·Experimental Gerontology·Jaciara Neves SousaSérgio Henrique Sousa Santos
Jul 9, 2021·Frontiers in Pharmacology·Qijing FanXiaoju Zou
Jul 31, 2020·Journal of Ethnopharmacology·Pei-Rong LinJason T C Tzen
Sep 11, 2012·Journal of Agricultural and Food Chemistry·Wan-hong DuXiao-Qing Zou

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