PMID: 9423719Jan 10, 1998Paper

Effect of pulsatile pressure on the breaking strength and movement of Prolene sutures

Journal of Vascular Surgery
P B DobrinR Mrkvicka

Abstract

Most studies of sutures used in vascular surgery have used steadily applied loads. But in vivo, sutures are subject to pulsatile pressures. Pulsatile pressures could weaken sutures, or they could be beneficial by helping to slide the suture, thereby equilibrating the tension between unevenly tightened loops. This study examined the effect of pulsatile pressures on the strength and movement of polypropylene (Prolene) sutures. Segments of pig thoracic aorta were cannulated and studied in a tissue bath in vitro at 37 degrees C. A longitudinal arteriotomy was made and then closed with running 6-0 Prolene. Vessels were subjected to (1) no pressure; (2) 100 mm Hg steady pressure; or (3) 112/65 mm Hg pulsatile pressure. After 48 hours the sutures were studied for breaking strength. In a second, separate set of experiments, longitudinal arteriotomies were closed using running suture lines. These were constructed with either several loose loops or several overly tight loops. Fine wires were affixed to the suture loops to permit photographic recording of suture movement. There was no difference in breaking force among 68 sutures that had been subjected to (1) no pressure; (2) 100 mm Hg steady pressure; or (3) 112/65 mm Hg pulsatile press...Continue Reading

References

Jul 1, 1988·Biomaterials·J A von FraunhoferB J Masterson
Mar 1, 1988·Journal of Vascular Surgery·P B Dobrin
Sep 1, 1987·American Journal of Surgery·R W LandymoreC A Cameron
Apr 1, 1985·The Annals of Thoracic Surgery·F Alajmo, M Vaccari
Mar 1, 1984·The Annals of Thoracic Surgery·V Aldrete
Feb 1, 1983·Journal of the American Podiatry Association·G V Yu, R Cavaliere
Mar 1, 1983·The Annals of Thoracic Surgery·R J Szarnicki
Jun 1, 1982·The Annals of Thoracic Surgery·G Cornel
Sep 1, 1981·Ophthalmology·H M Clayman
May 1, 1980·Journal of Biomedical Materials Research·H DahlkeK Thurau

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Citations

Nov 28, 2012·Computer Aided Surgery : Official Journal of the International Society for Computer Aided Surgery·Nenad FilipovicLazar Velicki
Apr 18, 2006·Journal of Materials Science. Materials in Medicine·Meng Deng, Jack Zhou
Mar 16, 2017·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Abigail E LonekerDenver M Faulk

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