Effect of radiofrequency catheter ablation for atrial fibrillation on left atrial cavity size

The American Journal of Cardiology
Laurens F TopsMartin J Schalij

Abstract

Left atrial (LA) remodeling is associated with atrial fibrillation (AF). Radiofrequency catheter ablation offers a good treatment option for AF, with reasonable long-term results. The purpose of the present study was to assess whether LA reverse remodeling occurs after successful catheter ablation. Fifty-seven consecutive patients (45 men; age 53 +/- 8 years) with symptomatic drug-refractory AF were treated with radiofrequency catheter ablation. The patients were divided into 2 groups on the basis of AF recurrence as determined by Holter monitoring and 12-lead electrocardiographic findings at 6 weeks and 3 months of follow-up (sinus rhythm [SR] group, no recurrence; AF group, AF recurrence). At baseline and 3 months of follow-up, 2-dimensional echocardiography was performed to assess LA size and dimensions. Furthermore, LA volumes were measured at end-systole and end-diastole. After 3 months, 39 of 57 patients (68%) maintained SR. At 3 months of follow-up, the LA anteroposterior diameter showed a significant reduction in the SR group (4.5+/- 0.3 vs 4.2 +/- 0.2 cm, p <0.01), and an additional increase was observed in the AF group (4.5+/- 0.3 vs 4.8 +/- 0.3 cm, p <0.05). Furthermore, the LA end-systolic and end-diastolic volumes ...Continue Reading

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