PMID: 2507590Sep 1, 1989Paper

Effect of radiotherapy on oral mucosa assessed by quantitative exfoliative cytology

Journal of Clinical Pathology
G R OgdenM W Green

Abstract

The effect of radiotherapy on normal buccal mucosa was investigated using the quantitative techniques of cytomorphology (measurement of nuclear and cytoplasmic area) and DNA cytophotometry. These techniques were applied to smears obtained before, during, and after irradiation. Nuclear area and cytoplasmic area increased and DNA values were abnormal in most cases as a result of radiotherapy, returning to within normal limits one month after treatment. This contrasts strongly with the changes seen in smears from previously irradiated uterine cervices, where changes in cytomorphology may persist for several years.

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Citations

Apr 1, 1993·European Journal of Cancer. Part B, Oral Oncology·H J GünzlK Donath
Feb 1, 1990·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·G R OgdenM W Green
Jan 26, 1991·BMJ : British Medical Journal·G R Ogden
Apr 1, 1993·Journal of Clinical Pathology·G R OgdenE B Lane
Feb 17, 2009·The Angle Orthodontist·Betina R PereiraElisa S Camargo
Dec 1, 1990·The British Journal of Oral & Maxillofacial Surgery·G R OgdenM W Green
Mar 21, 2006·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Zafer Ozgür PektasYildirim Karslioğlu
Dec 1, 1994·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·J B CourtI J Kerby
Aug 22, 2001·Cytopathology : Official Journal of the British Society for Clinical Cytology·N MollaogluR Walker
Sep 1, 1996·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·M R BrickleyJ P Shepherd
May 1, 1997·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·G R OgdenA J Wight
Jan 1, 1993·Cytopathology : Official Journal of the British Society for Clinical Cytology·J G CowpeM W Green
May 5, 1999·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·G R OgdenP Rice
Jun 10, 2015·The Journal of Contemporary Dental Practice·Deepika GopalB Thirupathi Reddy

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