Effect of randomization of mixtures of butter oil and vegetable oil on absorption and lipid metabolism in rats

European Journal of Nutrition
C BeckerG Hølmer

Abstract

The nutritional effect of the regiospecific distribution of fatty acids in edible fats is currently discussed due to an increased use of interesterification of fats for human consumption. However, disagreeing results have been reported which may be due to the varying composition of the dietary fats compared. Data on the fate of such lipids beyond the bloodstream is rather scarce and animal model studies are needed. To compare the metabolism of butter oil and mixtures of butter and rapeseed oil, native or randomized, in a rat model. The regiospecific fatty acid distribution present in dietary fats was followed through absorption, chylomicron formation, and deposition in adipose tissue and in different liver lipids (triacylglycerols, phosholipids, and cholesterol esters). Rats were fed for 6 weeks from weaning either butter oil (BO), a butteroil-rapeseed oil mixture 65:35 w/w (BR) or a randomized mixture of BR (tBR). Half of the animals were used for organ analysis, the rest for a postprandial study with the same fats and isolation of chylomicrons. The regiospecific distribution of the fatty acids present in the dietary fats was followed during metabolism by analyses of chylomicrons, depot fat and liver lipids, using regiospecifi...Continue Reading

Citations

Jan 20, 2005·Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology·Margaret H CooperHoracio Heras
Nov 8, 2014·Pest Management Science·María Concepción Velasco-HernándezNicolas Desneux
Aug 10, 2007·Journal of Agricultural and Food Chemistry·Trine PorsgaardHuiling Mu

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