PMID: 7336658Nov 1, 1981Paper

Effect of remantadine, ribavirin and their combinations on the protein synthesis of influenza virus A in a cell culture

Voprosy medit︠s︡inskoĭ khimii
N D L'vovG A Galegov

Abstract

Simultaneous use of ribavirin (I-beta-D-ribofuranosyl-1,2,4-triazol-3-carboxamide and rimantadine (alpha-methyl-I-adamantane methylamine HCL) was shown to effect most distinctly on protein synthesis in influenza virus A in the system studied as compared with the separate action of each of the drugs. Ribavirine inhibited the protein synthesis in rimantadine-resistant strain of influenza virus A.

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