PMID: 11929020Apr 4, 2002Paper

Effect of respiratory gating on reducing lung motion artifacts in PET imaging of lung cancer

Medical Physics
S A NehmehJ L Humm

Abstract

Positron emission tomography (PET) has shown an increase in both sensitivity and specificity over computed tomography (CT) in lung cancer. However, motion artifacts in the 18F fluorodioxydoglucose (FDG) PET images caused by respiration persists to be an important factor in degrading PET image quality and quantification. Motion artifacts lead to two major effects: First, it affects the accuracy of quantitation, producing a reduction of the measured standard uptake value (SUV). Second, the apparent lesion volume is overestimated. Both impact upon the usage of PET images for radiation treatment planning. The first affects the visibility, or contrast, of the lesion. The second results in an increase in the planning target volume, and consequently a greater radiation dose to the normal tissues. One way to compensate for this effect is by applying a multiple-frame capture technique. The PET data are then acquired in synchronization with the respiratory motion. Reduction in smearing due to gating was investigated in both phantoms and patient studies. Phantom studies showed a dependence of the reduction in smearing on the lesion size, the motion amplitude, and the number of bins used for data acquisition. These studies also showed an i...Continue Reading

References

May 1, 1995·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·T InoueD A Podoloff
Jan 1, 1996·Physics in Medicine and Biology·H D Kubo, B C Hill
Jun 23, 2000·International Journal of Radiation Oncology, Biology, Physics·S MinoharaM Kanazawa
Aug 22, 2000·European Journal of Nuclear Medicine·Y E ErdiE D Yorke
Oct 1, 2003·Clinical Positron Imaging : Official Journal of the Institute for Clinical P.E.T·Steven M. LarsonRobert Ginsberg

❮ Previous
Next ❯

Citations

Jan 22, 2003·European Journal of Nuclear Medicine and Molecular Imaging·Medhat M OsmanRichard L Wahl
May 16, 2003·European Journal of Nuclear Medicine and Molecular Imaging·D Visvikis, P J Ell
Jan 18, 2006·European Journal of Nuclear Medicine and Molecular Imaging·Lefteris LivieratosPaolo G Camici
Mar 21, 2007·European Journal of Nuclear Medicine and Molecular Imaging·Dale L BaileyRonnie Keijzers
Aug 7, 2008·European Journal of Nuclear Medicine and Molecular Imaging·Ralph A BundschuhMarkus Schwaiger
Sep 13, 2008·European Journal of Nuclear Medicine and Molecular Imaging·Doumit Daou
Jul 8, 2010·European Journal of Nuclear Medicine and Molecular Imaging·Florian BütherKlaus P Schäfers
Dec 15, 2012·European Journal of Nuclear Medicine and Molecular Imaging·Florian BütherKlaus P Schäfers
Feb 28, 2013·Journal of Pharmacokinetics and Pharmacodynamics·Giampaolo Tomasi, Eric O Aboagye
Aug 16, 2011·Molecular Imaging and Biology : MIB : the Official Publication of the Academy of Molecular Imaging·Giampaolo TomasiEric Aboagye
Jun 20, 2013·Molecular Imaging and Biology : MIB : the Official Publication of the Academy of Molecular Imaging·Parham GeramifarMohammad Reza Ay
Jul 1, 2010·International Journal of Computer Assisted Radiology and Surgery·Wai-Man PangPheng-Ann Heng
Feb 24, 2010·Annals of Nuclear Medicine·A M García VicenteV M Poblete García
Sep 16, 2010·Annals of Nuclear Medicine·Charalampos TsoumpasPaul K Marsden
Nov 15, 2011·Computers in Biology and Medicine·Quansheng XuDatian Ye
Nov 21, 2009·Physics in Medicine and Biology·Chi LiuPaul E Kinahan
May 25, 2004·Nuclear Medicine Communications·Kazuyoshi SugaNaofumi Matsunaga
Sep 24, 2004·The Cancer Journal·Jacqueline BrunettiCharles Vialotti
Dec 20, 2013·Nuclear Medicine Communications·Audrey PépinMarc-Etienne Meyer
Jul 25, 2007·AJR. American Journal of Roentgenology·Kazuyoshi SugaNaofumi Matsunaga
Nov 26, 2009·AJR. American Journal of Roentgenology·Matthias K WernerMatthew R Palmer
May 24, 2005·AJR. American Journal of Roentgenology·Yuji NakamotoMichio Senda
Sep 18, 2009·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Eric C FordRichard L Wahl
Mar 3, 2011·Medical Physics·S A NehmehJ L Humm
Apr 4, 2014·Medical Physics·Yoann PetibonGeorges El Fakhri
Aug 1, 2014·Biomedical Engineering Online·Michael FieselerKlaus P Schäfers
Jan 18, 2005·Medical Physics·S A NehmehJ L Humm
Nov 9, 2006·Medical Physics·Tinsu PanH A Macapinlac
Oct 9, 2012·Medical Physics·I PolycarpouP K Marsden
Dec 17, 2008·Medical Physics·Tinsu Pan, Osama Mawlawi

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.