PMID: 10222Aug 1, 1976

Effect of salts on the kinetic parameters and thermal stability of bovine brain acid phosphatase

General Pharmacology
H M Bittencourt, H Chaimovich


Bovine brain acid phosphatase is inhibited, at any pH, by an increase in ionic strength. The rate decrease is associated at pH 5, with a marked decrease in Km and, at pH 8, with a noticeable decrease in Vm. The rate of thermal inactivation of the enzyme is unaffected by increasing ionic strength up to 300 mM. These results are discussed in terms of interactions at the active site of the enzyme.


Jun 24, 1975·Biochimica Et Biophysica Acta·C E BaldijaoH Chaimovich
Feb 1, 1973·Analytical Biochemistry·G R Schacterle, R L Pollack
Sep 7, 1967·Biochemical and Biophysical Research Communications·Y TaniK Ogata
Jul 1, 1970·Archives of Biochemistry and Biophysics·H Chaimovich, F Nome
Oct 14, 1970·Biochimica Et Biophysica Acta·M IgarashiN Tsuyama
May 7, 1963·Biochimica Et Biophysica Acta·S SHIBKO, A L TAPPEL


Nov 23, 1977·Biochimica Et Biophysica Acta·M M TanizakiH Chaimovich

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