Effect of scrotal heating on sperm quality, seminal biochemical substances, and reproductive hormones in human fertile men

Journal of Cellular Biochemistry
Mei-Hua ZhangYi Qiu

Abstract

At present, male contraceptive methods are only vasectomy and condoms, so it is necessary to research on male contraceptive techniques. The aim of this study is to observe the effects of scrotal heating (SH) on semen parameters, seminal l-carnitine (LC), epidermal growth factor (EGF), macrophage migration inhibitory factor (MIF), reproductive hormones and sperm chromosome numbers of adult healthy men, and to provide the experimental data for male contraception. The scrotums of 30 healthy male volunteers were exposed to the condition of 40 to 43°C SH belt warming 40 minutes each day for successive 2 days per week. The course of SH was continuous for 3 months. Computer-assisted semen analysis and hypo-osmotic swelling test, sperm DNA integrity, l-carnitine, MIF and EGF, and sperm fluorescence in situ hybridization were performed before, during, and after SH. The serum level of follicle stimulating hormone (FSH), luteinizing hormone (LH), and testosterone (T) were measured by chemiluminescent immunoassay. The mean parameters of sperm concentration, vitality, and normal morphological sperm were significantly decreased in groups with sperms being collected during 1, 2, and 3 months of SH when compared with those in groups of pre-SH ...Continue Reading

References

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Aug 18, 2016·Animal Reproduction Science·Maria Sabés-AlsinaManel Lopez-Bejar

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Citations

Feb 14, 2021·Journal of Basic and Clinical Physiology and Pharmacology·Ravindran JegasothyRavichandran Jeganathan
Oct 27, 2020·Frontiers in Endocrinology·Robert John Aitken, Mark A Baker
Mar 25, 2021·American Journal of Men's Health·Zhi-Da ShiYi Qiu

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