PMID: 3745524Aug 1, 1986Paper

Effect of short-contact anthralin therapy on ultraviolet B irradiation of psoriasis

Journal of the American Academy of Dermatology
J Boer, G Smeenk

Abstract

The influence of short-contact anthralin on the therapeutic effect of ultraviolet B irradiation (Sylvania UV-21 tubes) was investigated with the half-body comparison method in fifteen outpatients with plaque-type psoriasis. The lesions on the right or left half of the body were exposed to one of the topically applied compounds (either anthralin and 2% salicylic acid in petrolatum or 2% salicylic acid in petrolatum alone) for 10 to 30 minutes daily. Of the fifteen patients, five (Group I) were given 0.3% anthralin and five (Group II) received increasing concentrations of anthralin (0.3, 1, 3%); the other five (Group III) were patients who had failed to respond to ultraviolet B therapy alone, and for them a new clearing treatment was started with the addition of anthralin in increasing concentrations (0.3%, 1%, 3%). Only two patients in Group I, one patient in Group II, and one in Group III showed a moderately better clearance of psoriasis on the short-contact anthralin side. Irritation of nonaffected skin by anthralin was common only during the first week of the treatment. Staining of clothes and bedding occurred.

References

Jan 1, 1984·The British Journal of Dermatology·A A SchothorstC A Kenter
Jan 1, 1984·Journal of the American Academy of Dermatology·N J LoweH Schaefer
Aug 1, 1983·The British Journal of Dermatology·J R MarsdenS Shuster
Aug 1, 1981·The British Journal of Dermatology·L Juhlin
Jan 1, 1980·Dermatologica·J BoerD Suurmond

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Citations

Feb 28, 2004·Journal of the American Academy of Dermatology·Mark LebwohlSteven R Feldman
Oct 6, 1997·Clinics in Dermatology·G Mahrle
Mar 25, 2000·The British Journal of Dermatology·R P SarkanyP G Norris
Feb 1, 1992·International Journal of Dermatology·L NaldiT Cainelli
Feb 18, 2012·International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·Christina RogalskiUwe Paasch
Jun 1, 1988·The British Journal of Dermatology·Y ParamsothyC M Lawrence
Jan 28, 2020·Expert Opinion on Drug Safety·Mio Nakamura, John Koo
Dec 22, 1999·Seminars in Cutaneous Medicine and Surgery·W L Morison
Feb 5, 1990·The Medical Journal of Australia·H Rotstein, C Baker

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