PMID: 9187034Apr 1, 1997Paper

Effect of simulated rain, coat length and exposure to natural climatic conditions on the efficacy of a topical formulation of eprinomectin against endoparasites of cattle

Veterinary Parasitology
R P GogolewskiJ S Eagleson

Abstract

A series of five controlled studies involving 114 cattle were conducted in Australia, North America and the United Kingdom to examine the effect of simulated rain, coat length and exposure to natural climatic conditions, on the efficacy of a topical formulation of eprinomectin against nematode parasites of cattle. In all trials infections were induced with a range of bovine nematode species and treatment was applied when the majority of nematodes were mature. In one study, simulated rain was applied to cattle ending one hour before treatment or beginning one, three or six hours after treatment. In a second study cattle had short (1 cm) or long (3-6 cm) haircoats at the time of treatment. Three other studies were conducted using cattle housed indoors or exposed to various natural climatic conditions. Nematode counts were determined using standard techniques and the efficacy of treatment was assessed relative to vehicle-treated controls. Regardless of the timing of simulated rain relative to treatment, eprinomectin was at least 99.9% effective (P < 0.01) against Haemonchus placei, Ostertagia ostertagi. Trichostrongylus axei and Cooperia spp. There were also no differences (p > 0.10) in efficacy between treatment administered to d...Continue Reading

References

Mar 1, 1992·Veterinary Parasitology·S RanjanD Carrier
Jun 1, 1992·Australian Veterinary Journal·J S Eagleson, G R Allerton
Mar 1, 1984·Journal of Veterinary Pharmacology and Therapeutics·W C Campbell, G W Benz
Sep 1, 1995·Veterinary Parasitology·W L ShoopM H Fisher
Jul 1, 1993·Veterinary Parasitology·R M JonesC D Smothers
Nov 1, 1996·International Journal for Parasitology·W L ShoopM J Turner
Jul 1, 1985·Parasitology Today·W C Campbell

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Citations

Jan 17, 2014·Journal of Parasitic Diseases : Official Organ of the Indian Society for Parasitology·T NazirAnish Yadav
Apr 1, 1997·New Zealand Veterinary Journal·R E PlueJ S Eagleson
Mar 22, 2005·Journal of the American Veterinary Medical Association·Keith J MertzWilliam B Epperson
Jul 15, 2016·Journal of Parasitic Diseases : Official Organ of the Indian Society for Parasitology·T NazirR Godara
Sep 8, 2011·Journal of Veterinary Pharmacology and Therapeutics·C GokbulutM Boyacioglu

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