PMID: 9170420Apr 15, 1997Paper

Effect of smoking on the clinical progression of HIV-1 infection

Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology : Official Publication of the International Retrovirology Association
N GalaiJ B Margolick

Abstract

Cigarette smoking as a risk factor in progression of HIV-1 disease was investigated in the Multicenter AIDS Cohort Study of homosexual men. Longitudinal data for T-cell subsets, HIV-related clinical symptoms, smoking behavior, and AIDS medication use were collected semiannually from 2,499 HIV-1-seropositive men for up to 9 years. Survival methods, including Kaplan-Meier analysis and multivariate Cox regression models, were used to assess the effect of cigarette smoking on development of Pneumocystis carinii pneumonia (PCP), AIDS, death, and self-reported oral thrush. After adjustment for CD4+ lymphocyte count and use of antiretroviral and anti-PCP medications, smoking was not significantly associated with progression to PCP, AIDS, or death in either the HIV-seroprevalent or-seroincident cohort members. Among men who had baseline CD4+ cell counts > 200/microliter, smoking was associated with a 40% increase in the hazard of oral thrush (p < or = 0.01). These data indicate that cigarette smoking does not have a major effect on the progression of HIV-1 infection to AIDS or death but may affect the incidence of oral thrush.

References

May 15, 1979·International Journal of Cancer. Journal International Du Cancer·M FersonP Hersey
Jan 1, 1988·Oral Surgery, Oral Medicine, and Oral Pathology·S SyrjänenA Ranki
Aug 1, 1995·American Journal of Epidemiology·J DudleyJ Chmiel
Feb 1, 1995·Obstetrical & Gynecological Survey·J BornsteinH Abramovici
Jan 1, 1995·Gynecologic and Obstetric Investigation·W A PoppeF A Van Assche
Aug 15, 1993·American Journal of Epidemiology·D R HooverH K Armenian

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Citations

Aug 9, 2005·Nicotine & Tobacco Research : Official Journal of the Society for Research on Nicotine and Tobacco·Jack E BurkhalterBruce D Rapkin
Dec 21, 2012·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Marie HellebergNiels Obel
Jul 14, 2006·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Donald E MercantePaul L Fidel
Dec 30, 2004·American Journal of Public Health·Gregory L GreenwoodRon Stall
Jun 30, 2007·American Journal of Public Health·Elisabeth P GruskinLarry L Bye
Jan 21, 2006·Journal of General Internal Medicine·Kristina CrothersAmy C Justice
Jun 27, 2009·AIDS Education and Prevention : Official Publication of the International Society for AIDS Education·Mariah M MarshallGregory D Kirk
Jun 27, 2009·AIDS Education and Prevention : Official Publication of the International Society for AIDS Education·Kristina CrothersAmy C Justice
Sep 21, 2010·American Journal of Respiratory and Critical Care Medicine·Kristina CrothersAmy C Justice
Jun 10, 2011·Proceedings of the American Thoracic Society·Shiva RahmanianPhilip Diaz
Jun 11, 2003·Chest·Philip T DiazThomas L Clanton
Aug 3, 2010·Infectious Disease Clinics of North America·Richard N van Zyl-SmitWing-Wai Yew
Aug 28, 2007·Clinics in Chest Medicine·Kristina Crothers
Oct 19, 2010·Journal of Neurochemistry·Vamshi K MandaPaul R Lockman
Dec 24, 2010·Journal of Internal Medicine·R HuttunenJ Syrjänen
Oct 4, 2012·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·Xiaoxu LiQianming Chen
Sep 27, 2016·The Canadian Journal of Statistics = Revue Canadienne De Statistique·Esra KürümRunze Li
Oct 11, 2014·BioMed Research International·Humidah AlanaziMahmoud Rouabhia
May 27, 2005·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Maria Jose Miguez-BurbanoGail Shor-Posner
Oct 6, 2000·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·R NiauraD B Abrams
Jan 29, 2000·International Journal of Dermatology·R Wolf, D Freedman
May 5, 2006·Advances in Dental Research·M M CooganL P Samaranayake
Aug 8, 2015·The European Respiratory Journal·Theresa M RossouwCharles Feldman
Aug 27, 2005·Oral Diseases·N S Soysa, A N B Ellepola
Apr 27, 2000·Current Opinion in Pulmonary Medicine·E A AshleyM C Lipman
Jul 28, 2015·Epidemiology·Jessie K EdwardsUNKNOWN CNICS
Feb 28, 2002·Oral Microbiology and Immunology·J SlavinskyPaul L Fidel
Feb 11, 1999·Oral Diseases·L L PattonJ J Eron
Sep 7, 2020·AIDS and Behavior·John M AbbamonteDeborah L Jones
Mar 19, 2002·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·J CampoA Bascones

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