Effect of spatial arrangement and structure of hierarchically patterned fibrous scaffolds generated by a femtosecond laser on cardiomyoblast behavior

Journal of Biomedical Materials Research. Part a
Indong JunHojeong Jeon

Abstract

Biological responses on biomaterials occur either on their surface or at the interface. Therefore, surface characterization is an essential step in the fabrication of ideal biomaterials for achieving effective control of the interaction between the material surface and the biological environment. Herein, we applied femtosecond laser ablation on electrospun fibrous scaffolds to fabricate various hierarchical patterns with a focus on the alignment of cells. We investigated the simultaneously stimulated response of cardiomyoblasts based on multiple topographical cues, including scales, oriented directions, and spatial arrangements, in the fibrous scaffolds. Our results demonstrated a synergistic effect on cell behaviors of one or more structural arrangements in a homogeneous orientation, whereas antagonistic effects were observed for cells arranged on a surface with heterogeneous directions. Taken together, these results indicate that our hierarchically patterned fibrous scaffolds may be useful tools for understanding the cellular behavior on fibrous scaffolds used to mimic an extracellular matrix-like environment. © 2018 Wiley Periodicals, Inc. J Biomed Mater Res Part A: 106A: 1732-1742, 2018.

References

Jun 1, 2002·Circulation Research·Kishore B S Pasumarthi, Loren J Field
Nov 4, 2008·Nature Materials·George C EngelmayrLisa E Freed
Dec 20, 2008·Nature Materials·Samir Mitragotri, Joerg Lahann
Feb 5, 2009·Nature Reviews. Molecular Cell Biology·John C Sparrow, Frieder Schöck
May 22, 2009·Nature Materials·Elsie S PlaceMolly M Stevens
Aug 25, 2009·Tissue Engineering. Part B, Reviews·Gordana Vunjak-NovakovicMilica Radisic
Jun 18, 2011·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Dan KaiSeeram Ramakrishna
Oct 21, 2011·Nature·Woo-Jae ChungSeung-Wuk Lee
Aug 25, 2012·Progress in Molecular Biology and Translational Science·Xiaohong WangJianyi Zhang
Oct 5, 2012·Development·Junji ItouYasuhiko Kawakami
Nov 17, 2012·Langmuir : the ACS Journal of Surfaces and Colloids·Yaowen LiuXiaohong Li
Nov 26, 2013·Biomaterials·Zhen MaKevin E Healy
Feb 6, 2014·Journal of Tissue Engineering and Regenerative Medicine·C SimitziA Ranella
Apr 18, 2014·Development, Growth & Differentiation·Takashi Takeuchi
Jun 1, 2013·Materials Today·Xianfeng WangBingyun Li
Oct 2, 2014·Advanced Drug Delivery Reviews·Christine A Cezar, David J Mooney
Oct 27, 2014·Nature Materials·Ulrike G K WegstRobert O Ritchie
Mar 24, 2015·Nature Communications·Ryan J WadeJason A Burdick
Apr 4, 2015·Optics Express·Shuhei Yada, Mitsuhiro Terakawa
Nov 13, 2015·Advanced Drug Delivery Reviews·Achilleas D TheocharisNikos K Karamanos
Dec 15, 2015·Advanced Drug Delivery Reviews·A K CapulliK K Parker
Jan 13, 2016·ACS Applied Materials & Interfaces·Suk Hee ParkKahp-Yang Suh
Jun 22, 2016·Cell and Tissue Research·Virpi Talman, Heikki Ruskoaho
Sep 11, 2016·Materials Science & Engineering. C, Materials for Biological Applications·M TallawiA R Boccaccini
Apr 19, 2017·Materials Science & Engineering. C, Materials for Biological Applications·Ewelina TomeckaZbigniew Brzozka
May 10, 2017·Biofabrication·Ch YiannakouE Stratakis
Jul 1, 2017·Soft Matter·Adrià SalesRalf Kemkemer
Jan 14, 2017·RSC Advances·S VaragnoloD Pisignano
Jul 21, 2015·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Bin SunYun-Ze Long
Jan 14, 2017·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Young Min ShinHeungsoo Shin

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Citations

Nov 2, 2021·Biomaterials Science·Oliver G FrostElena Garcia-Gareta

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