Effect of spinal cord signal intensity changes on clinical outcome after surgery for cervical spondylotic myelopathy

Journal of Neurosurgery. Spine
Anooj ChatleyRabi Narayan Sahu

Abstract

The presence of intramedullary T2 high signal intensity changes in patients with cervical spondylotic myelopathy (CSM) indicates the existence of a chronic spinal cord compressive lesion. However, the prognostic significance of signal intensity changes remains controversial. The purpose of this study was to evaluate the effect of spinal cord T2 signal intensity changes on the outcome after surgery for CSM. In a prospective study, 64 patients with CSM who underwent surgical treatment between October 2006 and April 2008 using an anterior approach were included. Based on the clinical symptoms and signs present, the severity of neurological deficits of all patients was scored according to a modified Japanese Orthopaedic Association scale score for CSM just before the surgery and at 6 months follow-up. Recovery rates were calculated at 6 months. There were 22 patients who did not have spinal cord intensity changes on MR imaging and 44 who demonstrated high-intensity signal changes on T2-weighted images (focal or segmental). No statistically significant differences were found in recovery rates between cases with T2 signal intensity changes and those with no signal intensity changes. However, the postoperative modified Japanese Orthop...Continue Reading

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Citations

Aug 3, 2012·European Journal of Nuclear Medicine and Molecular Imaging·Kenzo UchidaHisatoshi Baba
Jul 23, 2011·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Yong Eun ChoWoo Ho Cho
Mar 30, 2012·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Saumyajit Basu, Sreeramalingam Rathinavelu
Aug 29, 2012·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Aditya Vedantam, Vedantam Rajshekhar
May 23, 2014·Journal of the American Veterinary Medical Association·Joy A Delamaide GasperKenneth R Waller
Jun 22, 2014·The Spine Journal : Official Journal of the North American Spine Society·Daniel LubelskiThomas E Mroz
Jan 5, 2012·The British Journal of Radiology·R J V BartlettH Narayanamurthy
Oct 25, 2011·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·FengNing LiTiesheng Hou
Jun 24, 2011·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Peng ZhangLin-Feng Wang
Aug 25, 2010·The Veterinary Clinics of North America. Small Animal Practice·Ronaldo C da Costa
Aug 29, 2013·Veterinary Surgery : VS·John H RossmeislP Natalia Henao-Guerrero
Jul 15, 2016·British Journal of Neurosurgery·Kumbhar Kartik RevanappaVedantam Rajshekhar
Apr 26, 2013·Neurosurgery·Joseph C MaroonMatt El-Kadi

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