Effect of spinal sympathetic blockade upon local regulation of blood flow in subcutaneous tissue.

Acta Physiologica Scandinavica
O Henriksen, T Alsner

Abstract

The influence of spinal sympathetic blockade upon local regulation of blood flow in subcutaneous adipose tissue was investigated in six subjects. The effect of changes in orthostatic pressure on blood flow in subcutaneous tissue in the crus and distal forearm was measured before and after sympathetic blockade obtained by epidural anesthesia in 4 subjects and by a bilateral sympathectomy in 2 patients suffering from manual hyperhidrosis. Blood flow in subcutaneous tissue measured by 133Xe washout technique decreased by about 40 per cent when the limb was lowered, and remained constant during 30 cm elevation. This was found both before and after the blockade, though in one of the patients, the orthostatic decrease in blood flow was less pronounced 24 h after sympathectomy. Hence central sympathetic reflexes do not alter local orthostatic changes of blood flow in subcutaneous tissue. These changes therefore are most likely due to local mechanisms.

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Citations

Dec 13, 2002·Fertility and Sterility·Lian-Cheun FoongSoon-Chye Ng
Sep 1, 1976·Acta Physiologica Scandinavica·O HenriksenW Paaske
Jul 1, 1976·Acta Physiologica Scandinavica·O Henriksen
Aug 1, 1976·Acta Physiologica Scandinavica·O Henriksen
May 1, 1977·Acta Physiologica Scandinavica·O Henriksen, P Sejrsen
Jan 1, 1977·Acta Physiologica Scandinavica·O Henriksen, P Sejrsen
Jun 1, 1990·Scandinavian Journal of Clinical and Laboratory Investigation·R Jelnes
Nov 1, 1993·Journal of the American Academy of Dermatology·D W Pryce, P S Friedmann
Jun 26, 2007·The Journal of Foot and Ankle Surgery : Official Publication of the American College of Foot and Ankle Surgeons·Fahad AttarN P Geary
Nov 1, 1986·Acta Oto-laryngologica·P Olsson, M Bende
Oct 1, 1976·Acta Physiologica Scandinavica·L Henriksen, P Sejrsen
Jul 15, 2006·The Journal of Physiological Sciences : JPS·Fumio YamazakiRyoko Sone
Feb 25, 2000·BJOG : an International Journal of Obstetrics and Gynaecology·L C FoongR W Beard
Nov 5, 1976·Pflügers Archiv : European journal of physiology·O HartlingJ Trap-Jensen

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