Effect of stannous fluoride and zinc phosphate dentifrice on dental plaque and gingivitis: A randomized clinical trial with 6-month follow-up

The Journal of the American Dental Association
Dutmanee SeriwatanachaiYun-Po Zhang

Abstract

The objective of this study was to compare a stabilized stannous fluoride (SnF2) dentifrice with zinc phosphate (Colgate TotalSF) with SnF2 with zinc lactate and control fluoride dentifrices for gingivitis and plaque control over a 6-month period. A total of 135 adult participants were enrolled in this study. After randomization and blinding of examiners and patients, enrolled participants were provided instructions for use of assigned dentifrice. At 3 visits (0, 3, and 6 months), various gingival and plaque indexes were collected to determine the clinical efficacy of a stabilized SnF2 dentifrice. These results were compared with a SnF2 with zinc lactate dentifrice and with a control fluoride dentifrice. A total of 135 participants completed the study. All groups reported statistically significant reductions in gingival inflammation and improvement in plaque control at 3- and 6-month follow-up. Both SnF2 dentifrices showed statistically significant reductions in all indexes compared with the control dentifrice (P < .001). However, the test dentifrice showed higher but nonsignificant improvements in plaque and gingival indexes compared with the other SnF2 dentifrice. This study reports similar efficacy of a test dentifrice to a ...Continue Reading

Citations

Sep 4, 2020·Biomimetics·Luca FiorilloMarco Cicciù
May 1, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Meenakshi RajendiranLin Chen
Mar 26, 2021·Journal of Breath Research·Marianne ZsiskaJulie Grender

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