PMID: 6539717Apr 1, 1984Paper

Effect of streptozotocin-induced hyperglycaemia on androgen-binding protein in rat testis and epididymis

Diabetologia
N Kühn-VeltenW Staib

Abstract

In adult male rats treated with streptozotocin 6 weeks before the experiments, androgen-binding protein concentration was increased in testicular tissue by 33% (p less than 0.01) and reduced in epididymal tissue by 25% (p less than 0.005) in animals exhibiting severe hyperglycaemia as compared with animals remaining in normoglycaemia or moderate hyperglycaemia. Androgen-binding protein content was diminished in epididymal tissue by 40% (p less than 0.0005) but not changed in testicular tissue. If related to constant body weight, the sum of testicular and epididymal androgen-binding protein was identical in both normo- and hyperglycaemic animals. This disturbance in androgen-binding protein distribution may be the consequence of altered testicular secretion or impaired transport of androgen-binding protein from testes to epididymides.

Citations

Dec 20, 2011·Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology·Nermin A H SadikOlfat G Shaker
Nov 7, 2009·Andrologia·G RicciM Galdieri
Mar 26, 2014·Tissue Barriers·Marco G AlvesPedro F Oliveira
Dec 3, 2014·Acta histochemica·Guruswami Gurusubramanian, Vikas Kumar Roy
Mar 10, 2006·International Journal of Andrology·W R ScaranoW G Kempinas

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