Effect of subinhibitory concentrations of cumin (Cuminum cyminum L.) seed essential oil and alcoholic extract on the morphology, capsule expression and urease activity of Klebsiella pneumoniae

International Journal of Antimicrobial Agents
Safoura DerakhshanMohsen Bigdeli

Abstract

Cuminum cyminum L., commonly known as cumin, is a plant with a considerable reputation. The aim of this work was to study the activity of cumin seed essential oil and alcoholic extract against Klebsiella pneumoniae ATCC 13883 and clinical K. pneumoniae isolates by evaluating the effect of subminimum inhibitory concentrations (sub-MICs) on cell morphology, capsule expression and urease activity. Growth of K. pneumoniae strains exposed to sub-MICs of C. cyminum extracts resulted in cell elongation and repression of capsule expression. Urease activity was decreased. The major constituent of the oil determined by gas chromatography/mass spectrometry was cumin aldehyde.

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Citations

Nov 19, 2011·Pharmacognosy Reviews·R K Johri
Oct 10, 2014·BioMed Research International·Abhinav UpadhyayKumar Venkitanarayanan
Mar 30, 2013·Phytomedicine : International Journal of Phytotherapy and Phytopharmacology·Su-Hyun MunDong-Yeul Kwon
Apr 22, 2016·Jundishapur Journal of Microbiology·Auttawit SirichoatAroonlug Lulitanond
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Feb 17, 2015·Journal of Advanced Research·Luzia V ModoloÂngelo de Fátima
Aug 16, 2016·Applied and Environmental Microbiology·Judit K KovácsGyörgy Schneider
Mar 22, 2019·Current Protein & Peptide Science·Ritu Kataria, Anurag Khatkar
Jul 19, 2020·Biomolecules·Othmane MerahAkram Hijazi
Aug 8, 2020·Antibiotics·Hana Mohammed Al AlSheikhQazi Mohd Rizwanul Haq
Dec 18, 2020·International Journal of Systematic and Evolutionary Microbiology·Ye-Ji HwangSa-Youl Ghim
Oct 22, 2020·European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences·Noura H Abd EllahBasma N Abd El-Hamid

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